ID A0A1F6WNC9_9BACT Unreviewed; 557 AA.
AC A0A1F6WNC9;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Penicillin-binding protein 2 {ECO:0008006|Google:ProtNLM};
GN ORFNames=A2997_01540 {ECO:0000313|EMBL:OGI83389.1};
OS Candidatus Nomurabacteria bacterium RIFCSPLOWO2_01_FULL_36_10b.
OC Bacteria; Candidatus Nomurabacteria.
OX NCBI_TaxID=1801766 {ECO:0000313|EMBL:OGI83389.1, ECO:0000313|Proteomes:UP000179448};
RN [1] {ECO:0000313|EMBL:OGI83389.1, ECO:0000313|Proteomes:UP000179448}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGI83389.1}.
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DR EMBL; MFUQ01000018; OGI83389.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F6WNC9; -.
DR STRING; 1801766.A2997_01540; -.
DR Proteomes; UP000179448; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF24; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE PBPA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 47..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 118..182
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 226..535
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 557 AA; 62161 MW; 1F72E496CD1AA226 CRC64;
MRRSYFTKHA KHAEISPDEI FLDSSNVSSF DEQQLEGFIE RPLPKRIFIL VGLIVITVLF
LFFVQLIRLQ VFQGHEYARL AENNRVNRIT LFSERGIIYD RFNVKLAWNE ESENSEPFSR
REYINKEGFG HLLGYISYPK KDSNNIYWQD SIIGREGVEH IFNKQLQGIH GAILQETDAR
SNSTSVVGMI NPEPGDNITL SIDSRIQSAL AESIEYMVEQ FDYKAGSGII MDIHTGEIIA
ITNVPEYNPM ILSEGIDTTR IKEYLTSKSG YFINRAISGL YTPGSIIKPF IALAALQEEA
INEWTTILST GQIEVPNPYD KNKPSIYRDW KSDGHGVVGV KDALANSVNT FFYAIVGGYR
GQKGIGIDVL NKYVELFEIG SSTKSIFPHE ADGTIPSPKW KKKVFNEPWR LGDTYITAIG
QFGFQVTPIQ MVRATSAIAN GGILLIPHII AGETTVSQII SGINPNNYNI VREGMRKTVT
GGTATVLNIS NPHIAAKTGT AQVGALRNQV NSWVIGFYPY EDPQYAFTVV MEKGPSVGIV
GASWAIRHMF DILAVLP
//
