ID A0A1F6XIH0_9BACT Unreviewed; 340 AA.
AC A0A1F6XIH0;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE RecName: Full=HMA domain-containing protein {ECO:0000259|PROSITE:PS50846};
GN ORFNames=A3A03_03660 {ECO:0000313|EMBL:OGI93935.1};
OS Candidatus Nomurabacteria bacterium RIFCSPLOWO2_01_FULL_40_18.
OC Bacteria; Candidatus Nomurabacteria.
OX NCBI_TaxID=1801773 {ECO:0000313|EMBL:OGI93935.1, ECO:0000313|Proteomes:UP000176629};
RN [1] {ECO:0000313|EMBL:OGI93935.1, ECO:0000313|Proteomes:UP000176629}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGI93935.1}.
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DR EMBL; MFUX01000035; OGI93935.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F6XIH0; -.
DR STRING; 1801773.A3A03_03660; -.
DR Proteomes; UP000176629; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd00371; HMA; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR InterPro; IPR006121; HMA_dom.
DR InterPro; IPR036163; HMA_dom_sf.
DR InterPro; IPR039447; UreH-like_TM_dom.
DR PANTHER; PTHR42208; HEAVY METAL TRANSPORTER-RELATED; 1.
DR PANTHER; PTHR42208:SF1; HEAVY METAL TRANSPORTER-RELATED; 1.
DR Pfam; PF13386; DsbD_2; 1.
DR Pfam; PF00403; HMA; 1.
DR SUPFAM; SSF55008; HMA, heavy metal-associated domain; 1.
DR PROSITE; PS50846; HMA_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 85..103
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 123..143
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 164..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 195..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 240..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 271..295
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 307..334
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 3..72
FT /note="HMA"
FT /evidence="ECO:0000259|PROSITE:PS50846"
SQ SEQUENCE 340 AA; 36310 MW; A2AF70A687DCF25A CRC64;
MLKKYTFHVI GTHCPACKIL IEDILKEQSV VKNVRVNLKR ETVEIETDSE KNPEELAQIL
TSKIKPNGYT LSIEKNIQEQ KSNDVIWKAI PIGLAFLVLF FILQKSGILN LSIGGKTTPA
TSFIVGLIAS VSSCLAIVGG LVLSLSAKIS QDDAKENISD TKTYLLFHTG RLVSFALLGG
LLGIIGNAIG INFTFAAILG IIASLVMITL GLNLTGVFSK NRIALPGGIF NFFRKIEHKT
LTPLIIGFAT FFLPCGFTQS MQVVAISSGS FISGMLIMLS FALGTLPVLL LLSFGSASFA
HGKHAPLFFK SAGVIVLGLG LFALLAGLAG LGIINPLFNI
//
