ID A0A1F6XNI8_9BACT Unreviewed; 568 AA.
AC A0A1F6XNI8;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=Lipid II flippase MurJ {ECO:0008006|Google:ProtNLM};
GN ORFNames=A2917_00070 {ECO:0000313|EMBL:OGI95706.1};
OS Candidatus Nomurabacteria bacterium RIFCSPLOWO2_01_FULL_42_17.
OC Bacteria; Candidatus Nomurabacteria.
OX NCBI_TaxID=1801780 {ECO:0000313|EMBL:OGI95706.1, ECO:0000313|Proteomes:UP000178104};
RN [1] {ECO:0000313|EMBL:OGI95706.1, ECO:0000313|Proteomes:UP000178104}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGI95706.1}.
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DR EMBL; MFVE01000002; OGI95706.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F6XNI8; -.
DR STRING; 1801780.A2917_00070; -.
DR Proteomes; UP000178104; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR InterPro; IPR004268; MurJ.
DR PANTHER; PTHR47019; LIPID II FLIPPASE MURJ; 1.
DR PANTHER; PTHR47019:SF1; LIPID II FLIPPASE MURJ; 1.
DR Pfam; PF03023; MurJ; 1.
DR PRINTS; PR01806; VIRFACTRMVIN.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cell shape {ECO:0000256|ARBA:ARBA00022960};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Peptidoglycan synthesis {ECO:0000256|ARBA:ARBA00022984};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 62..82
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 103..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 143..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 168..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 195..215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 263..286
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 292..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 331..355
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 367..390
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 402..423
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 447..469
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 490..509
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 515..539
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 568 AA; 62845 MW; 9E155398CB07062A CRC64;
MEKLLKIFNK ESVNINQAAL LLGFFTMLSQ VLALFRDRAI AHFVGPSSSL DAYYAAFRVP
DLIFISIASL ASFTVIIPFI VARMQGGIVT DRARKFLNDV FTVFLMVMVL VSVVAFFLMP
YLAEVIAPGF TPLLQAKVVM LSRIMLLSPI LLGLSNLFGA VTQIFQKFFI YALSPIFYNF
GIIIGVIFIY PVFGIYGLAV GVALGAFMHF VIQVISARSC GFTPKFSLRL FRLFGLFDIN
FADIKSAVLT SLPRTFGLAF NNIALISIIA LASYLTSGSI SLFNLAFSLQ SVPLNIIGIS
YAVAAFPTLA KSFSLGRMDE FKNHLKSAAR AVVFWSLPVI FLFIVVRAQI VRVILGSGSF
SWDNTRLVAA CLAVFSVSIL AQGMITLLSR AYYAKGDTKR PLIVNFACAI LIIILSFFFT
HLFQNMPMFR FFIESLLKVG NIPGTEVLML PLAYSVGTII NAVLQWFFVR RDFMQGESFI
TKTFFQSLGA SFFLGLTAYI GLNILSPIFG TTTFWGVFLQ GFISGILGII AAILVLHLLK
NEELSDLTRT LKTKFWRAKI IAPSQEGL
//
