ID A0A1F7ALJ0_9BACT Unreviewed; 191 AA.
AC A0A1F7ALJ0;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Thymidylate kinase-like domain-containing protein {ECO:0000259|Pfam:PF02223};
GN ORFNames=A3J23_02275 {ECO:0000313|EMBL:OGJ46289.1};
OS Candidatus Peregrinibacteria bacterium RIFCSPLOWO2_02_FULL_48_14.
OC Bacteria; Candidatus Peregrinibacteria.
OX NCBI_TaxID=1801900 {ECO:0000313|EMBL:OGJ46289.1, ECO:0000313|Proteomes:UP000177381};
RN [1] {ECO:0000313|EMBL:OGJ46289.1, ECO:0000313|Proteomes:UP000177381}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + dTMP = ADP + dTDP; Xref=Rhea:RHEA:13517,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:58369, ChEBI:CHEBI:63528,
CC ChEBI:CHEBI:456216; EC=2.7.4.9;
CC Evidence={ECO:0000256|ARBA:ARBA00001008};
CC -!- SIMILARITY: Belongs to the thymidylate kinase family.
CC {ECO:0000256|ARBA:ARBA00009776}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGJ46289.1}.
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DR EMBL; MFXD01000008; OGJ46289.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F7ALJ0; -.
DR STRING; 1801900.A3J23_02275; -.
DR Proteomes; UP000177381; Unassembled WGS sequence.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039430; Thymidylate_kin-like_dom.
DR PANTHER; PTHR10344; THYMIDYLATE KINASE; 1.
DR PANTHER; PTHR10344:SF4; THYMIDYLATE KINASE; 1.
DR Pfam; PF02223; Thymidylate_kin; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 7..177
FT /note="Thymidylate kinase-like"
FT /evidence="ECO:0000259|Pfam:PF02223"
SQ SEQUENCE 191 AA; 21986 MW; 4E0EE2AADD5BD816 CRC64;
MFITLYGINN IGKSTQALRL VERLKAEGFD AVYVKFPVYD VEPTGVYLNQ FLRSGEAQNI
SEEELQMWFA MNRFQFEPTL REWLKDGKVV VAEDYTGTGI AWGMVKGASK EWLESLNRPL
IKEDLAVLLD GERFVHATEE GHIHETNEEF MKLARQIHLE LGEAYGWVKI PVQPTKDETE
ALVWEVVKVH I
//
