ID   A0A1F7CNR6_9BACT        Unreviewed;       560 AA.
AC   A0A1F7CNR6;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=TGS domain-containing protein {ECO:0000259|PROSITE:PS51880};
GN   ORFNames=A3H22_03980 {ECO:0000313|EMBL:OGJ71448.1};
OS   Candidatus Peribacteria bacterium RIFCSPLOWO2_12_FULL_55_15.
OC   Bacteria; Candidatus Peregrinibacteria; Candidatus Peribacteria.
OX   NCBI_TaxID=1801931 {ECO:0000313|EMBL:OGJ71448.1, ECO:0000313|Proteomes:UP000182940};
RN   [1] {ECO:0000313|EMBL:OGJ71448.1, ECO:0000313|Proteomes:UP000182940}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=27774985; DOI=10.1038/ncomms13219;
RA   Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA   Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA   Williams K.H., Hubbard S.S., Banfield J.F.;
RT   "Thousands of microbial genomes shed light on interconnected biogeochemical
RT   processes in an aquifer system.";
RL   Nat. Commun. 7:13219-13219(2016).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OGJ71448.1}.
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DR   EMBL; MFYG01000008; OGJ71448.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1F7CNR6; -.
DR   STRING; 1801931.A3H22_03980; -.
DR   Proteomes; UP000182940; Unassembled WGS sequence.
DR   GO; GO:0015969; P:guanosine tetraphosphate metabolic process; IEA:InterPro.
DR   CDD; cd05399; NT_Rel-Spo_like; 1.
DR   CDD; cd01668; TGS_RSH; 1.
DR   Gene3D; 3.10.20.30; -; 1.
DR   Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR   Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR   InterPro; IPR012675; Beta-grasp_dom_sf.
DR   InterPro; IPR043519; NT_sf.
DR   InterPro; IPR007685; RelA_SpoT.
DR   InterPro; IPR004095; TGS.
DR   InterPro; IPR012676; TGS-like.
DR   InterPro; IPR033655; TGS_RelA/SpoT.
DR   PANTHER; PTHR21262:SF31; BIFUNCTIONAL (P)PPGPP SYNTHASE_HYDROLASE SPOT; 1.
DR   PANTHER; PTHR21262; GUANOSINE-3',5'-BIS DIPHOSPHATE 3'-PYROPHOSPHOHYDROLASE; 1.
DR   Pfam; PF13328; HD_4; 1.
DR   Pfam; PF04607; RelA_SpoT; 1.
DR   Pfam; PF02824; TGS; 1.
DR   SMART; SM00954; RelA_SpoT; 1.
DR   SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR   SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR   SUPFAM; SSF81271; TGS-like; 1.
DR   PROSITE; PS51880; TGS; 1.
PE   4: Predicted;
FT   DOMAIN          354..416
FT                   /note="TGS"
FT                   /evidence="ECO:0000259|PROSITE:PS51880"
SQ   SEQUENCE   560 AA;  62694 MW;  EAC61059E810C677 CRC64;
     MPFPTFAQSP RIQRAFLTAR EAYGDGLHWT GVSLSAHVLG VLRALQPFGP DEDAMIACLL
     HHLLQVPFWN AERLKREYGE RVQAMVRGIH LLSHVTLRDR RLPVERLRAM LVRVADDMRV
     LLIILCDRCH VLDALHSLPA AEQRRVCQDA LHLFAPAAAR LGIFSLKNRI ESLAFPVVYP
     ADAERITEQL TSLHCQYGAF LPVASAALRV FLEEQGMVTS VEVREKQPYS IFMKMRAKGM
     TAVSAVYDLF AFRVTVRSPE ECYQVLGHLH NRGHPIPNRF KDYLAFPKPN GYRSLHTTLT
     QLPCVPPGVF IEVQVRTEEM AYEAEYGVAS HWQYKESGPS AEATRRVQKL LACQPGIFVL
     TPKGDIVELP DGATPLDFAF QVHSTLGLSF RAARVNGVIA PLTHHLENGD VVEVIRHRDP
     RPSPRWMQYL HTAEARSKLR RFIAERDAVR DGVAPAPSPR HVPSLRATSS SIASVSALPS
     RRPSAPHHCK AIPVTVGGGL DFPLSYALCC HPEEKRGGTI AGVVTRLGRV RIHHHGCRML
     AHVHPDRRIE VQWDWEGIGD
//