ID A0A1F7GBH8_9BACT Unreviewed; 539 AA.
AC A0A1F7GBH8;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 13-SEP-2023, entry version 13.
DE RecName: Full=Penicillin-binding protein 2 {ECO:0008006|Google:ProtNLM};
GN ORFNames=A2774_02725 {ECO:0000313|EMBL:OGK15922.1};
OS Candidatus Roizmanbacteria bacterium RIFCSPHIGHO2_01_FULL_39_12c.
OC Bacteria; Candidatus Roizmanbacteria.
OX NCBI_TaxID=1802031 {ECO:0000313|EMBL:OGK15922.1, ECO:0000313|Proteomes:UP000177208};
RN [1] {ECO:0000313|EMBL:OGK15922.1, ECO:0000313|Proteomes:UP000177208}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGK15922.1}.
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DR EMBL; MFZG01000029; OGK15922.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F7GBH8; -.
DR Proteomes; UP000177208; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 27..48
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 103..178
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 211..532
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 539 AA; 60287 MW; DB0CEC6007CCC7BD CRC64;
MDKLPIFTKA GSQNIHFAGR RRISSQVLLY LYLCFTLILF FVLTLRLFQL TIVKGNYYRQ
LSEDNRIKEL MIESQRGKIL DRKGMVVAEN NPADQEKNSE RLTSSRIYHF SEEVAHLLGY
RQKADKYDLK NDSCLNKLKI GDKTGKKGVE KLFDCALRGR HGKKLIEVDA KGSYLRTLSL
SPPTGGLTIQ LALDLGLQKK AYELIKEKRA SVIATVPKTG EILILASSPS FNLQSFENED
QAITASYLHD ENKPLFNRTT EGTYPPGSIF KLVLAAGALE EEKIDAKTEF EDTGVLKAGP
LEFGNWYFLQ YGKTDGMVDI IKGIRRSNDI FFYKTGELLT PEKIKKWGET LGYGSITRIG
VTESDGLIPS PFWKEEKIRD RWYLGDTYNL SIGQGYLLVT PLQVNMTTAV FANGGYLCKP
ELLKVQSLKS NPPAGGQNCK KLPISDKTLQ LIRQGMKEAC SAGGTGWPLF DFQPKVACKT
GTAESHGNNA DPHAWFTVFA PFENPEIALT VLVENSGQGS DIAAPIAKEI LKMYFERKE
//
