ID A0A1F7IEJ3_9BACT Unreviewed; 551 AA.
AC A0A1F7IEJ3;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Penicillin-binding protein transpeptidase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=A2954_03630 {ECO:0000313|EMBL:OGK41780.1};
OS Candidatus Roizmanbacteria bacterium RIFCSPLOWO2_01_FULL_37_12.
OC Bacteria; Candidatus Roizmanbacteria.
OX NCBI_TaxID=1802056 {ECO:0000313|EMBL:OGK41780.1, ECO:0000313|Proteomes:UP000177698};
RN [1] {ECO:0000313|EMBL:OGK41780.1, ECO:0000313|Proteomes:UP000177698}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGK41780.1}.
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DR EMBL; MGAG01000009; OGK41780.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F7IEJ3; -.
DR STRING; 1802056.A2954_03630; -.
DR Proteomes; UP000177698; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 43..191
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 235..538
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 551 AA; 61707 MW; 0F065F819C6033CD CRC64;
MSKQKLLFIV FFLSYVAIIV KLIFLQIINP ISSDANYLKT SRIVPERGKI YDKNGEPMAV
NKSSYLFYIE PKKIKDTKEF VKRVDAVLQM GEASLEAKVD SNKNWIAVKD GLDRTQKQSL
QDLGLNGLGF EDRFQRSYPE SSLSAHLLGF VGKDSQGENL GYFGIEGYYN KDLVGLPGIL
KSDRDLLGRP ILIGTQQKLD SENGRDLFLT IDKPVQEIIK TRLRKGLEKY KAKEGCILLV
NPQTLEVLAL SCLPDFDVEH YYNFSEEFFK NPAISNLYEP GSTFKPLILA AALEENSVRP
ADFYDEKGPV QIGEYTIKTW DDKYEGRISL TRILEKSSNV GMVHVGQQLG QKKIFAYLKK
YGFDRPTGID LQGESYGNLK PETAWYPIDF ATVSFGQGIA ITPIQMIRAF AVLVNGGKMF
KPYIVQKIGS GEDEKNISSK LEKQVISAKT SETIKKMLLS AVENGEIRWA KPKGYQIAGK
TGTAQIPIKG HYDPTKTVAS FIGFAPVSNP KFLALVILRE PESSPWGSET AAPLFFDVAK
ELLVYYNIAP E
//
