ID A0A1F7INC7_9BACT Unreviewed; 552 AA.
AC A0A1F7INC7;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=Penicillin-binding protein 2 {ECO:0008006|Google:ProtNLM};
GN ORFNames=A2957_02640 {ECO:0000313|EMBL:OGK44895.1};
OS Candidatus Roizmanbacteria bacterium RIFCSPLOWO2_01_FULL_38_11.
OC Bacteria; Candidatus Roizmanbacteria.
OX NCBI_TaxID=1802060 {ECO:0000313|EMBL:OGK44895.1, ECO:0000313|Proteomes:UP000179072};
RN [1] {ECO:0000313|EMBL:OGK44895.1, ECO:0000313|Proteomes:UP000179072}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGK44895.1}.
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DR EMBL; MGAK01000010; OGK44895.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F7INC7; -.
DR STRING; 1802060.A2957_02640; -.
DR Proteomes; UP000179072; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 43..191
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 235..538
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 552 AA; 62256 MW; 3636C5739022FCFF CRC64;
MKRLFTLFVF FLFTVFAILI KLFYIQAFSG DTYSGNYLRT TRIAPVRGII FDRNKEPLVI
NQSSYTLFAE PKNLEDSFNT LKEIDSILNI GEATLEGRFD KSKDWVALAR NLEEDQKKKL
EKLNIHGLGF DEYSKRYYPE ASIAAHLVGF VGKDEDGDDI GYFGVEGYYD KDLQGLPGLL
KTERDILGRP IVIGTQNKLK GENGRDFVLT IDKRTQKMAK EAIEKAIEVY KAQSGCITII
EPNTGEILAM DCAPDFDPSE YFKFNESFFK NPVISDVFEP GSIIKPLWVA AALNEQKIKS
YDMYDEKGPI NIGKYYIRTW DNKYHGDISI TQILQQSSNV GMVFVGDKLG EENIKKYLKA
YGFGEKTNID LQGEVSSYLR KDSQWRPIDF ATVTFGQGIV VTQIQMLKAF SVLVNGGWVV
EPHVVKEMVS ESGDAKKIAP KKEKRILTEK TSRTIRQMLY ETVNHGEAKW NIPKGYKIGG
KTGTAQIAIQ GAYDASKTNA SFIGFGPVDN PKFLVLVTLN QPQTSPWASE TSAPVFFEVA
RDLLVQYNIP PK
//
