ID A0A1F7JCB3_9BACT Unreviewed; 281 AA.
AC A0A1F7JCB3;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Lysine biosynthesis enzyme LysX {ECO:0000313|EMBL:OGK53252.1};
GN ORFNames=A3H78_03015 {ECO:0000313|EMBL:OGK53252.1};
OS Candidatus Roizmanbacteria bacterium RIFCSPLOWO2_02_FULL_36_11.
OC Bacteria; Candidatus Roizmanbacteria.
OX NCBI_TaxID=1802071 {ECO:0000313|EMBL:OGK53252.1, ECO:0000313|Proteomes:UP000177418};
RN [1] {ECO:0000313|EMBL:OGK53252.1, ECO:0000313|Proteomes:UP000177418}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- PATHWAY: Amino-acid biosynthesis. {ECO:0000256|ARBA:ARBA00029440}.
CC -!- SIMILARITY: Belongs to the RimK family. LysX subfamily.
CC {ECO:0000256|ARBA:ARBA00006239}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGK53252.1}.
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DR EMBL; MGAV01000021; OGK53252.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F7JCB3; -.
DR Proteomes; UP000177418; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0009085; P:lysine biosynthetic process; IEA:InterPro.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR Gene3D; 3.40.50.20; -; 1.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR InterPro; IPR011761; ATP-grasp.
DR InterPro; IPR013651; ATP-grasp_RimK-type.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR011870; LysX_arch.
DR InterPro; IPR016185; PreATP-grasp_dom_sf.
DR InterPro; IPR004666; Rp_bS6_RimK/Lys_biosynth_LsyX.
DR NCBIfam; TIGR02144; LysX_arch; 1.
DR NCBIfam; TIGR00768; rimK_fam; 1.
DR PANTHER; PTHR21621:SF0; BETA-CITRYLGLUTAMATE SYNTHASE B-RELATED; 1.
DR PANTHER; PTHR21621; RIBOSOMAL PROTEIN S6 MODIFICATION PROTEIN; 1.
DR Pfam; PF08443; RimK; 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR SUPFAM; SSF52440; PreATP-grasp domain; 1.
DR PROSITE; PS50975; ATP_GRASP; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00409}.
FT DOMAIN 90..274
FT /note="ATP-grasp"
FT /evidence="ECO:0000259|PROSITE:PS50975"
SQ SEQUENCE 281 AA; 31115 MW; 986F65E3EC2F5E2A CRC64;
MVIGLLHTTI RTDEKLLIEA AKKRNVKMML IDVRESAFLP SILYNFDVVL ERCVSTTKGN
YAISFFESLN IPVVNSSRVA AICEDKFLTS LALYKNKVKE PQFAMVFNID QAVITIEKMG
GYPVVIKPTK GSWGRLLAKV NDSDALETIL EHKTVLGSPQ HKAFYIQQYI DKAGVDIRAF
VIDGVVISAI SRRSDHWITN TARGGSVENY HVTQSLQDIC KSASYAVGGG VLAIDLMETD
SGYLVNEINH TMEFKNSEIP TGVSISGAII DYCLKIINKK C
//
