ID A0A1F7L068_9BACT Unreviewed; 550 AA.
AC A0A1F7L068;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Penicillin-binding protein transpeptidase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=A3K52_01855 {ECO:0000313|EMBL:OGK73517.1};
OS Candidatus Roizmanbacteria bacterium RIFOXYD1_FULL_38_12.
OC Bacteria; Candidatus Roizmanbacteria.
OX NCBI_TaxID=1802093 {ECO:0000313|EMBL:OGK73517.1, ECO:0000313|Proteomes:UP000177050};
RN [1] {ECO:0000313|EMBL:OGK73517.1, ECO:0000313|Proteomes:UP000177050}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGK73517.1}.
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DR EMBL; MGBR01000001; OGK73517.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F7L068; -.
DR Proteomes; UP000177050; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 41..183
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 234..537
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 550 AA; 61957 MW; 88701EBB4CFD2FEB CRC64;
MTKLRFLLFL FFLFYIGIIV RLFFIQVLRP STSADYLRTR KIPPERGKIL DRNNQPLVTN
QTKYQLYLEP KNIDDEEILK IKLSRELQVE ESSISSKLDR SKEWIALYSG ITKEKHDAIN
ALKLSGVGFN EEQSRYYPEG SSSAHLLGFV GKNQGGENIG YFGIEGFYDK DLSGFPGLIR
SDRDLIDRPI FLGTQERIDP ENGRDLVLTV DKTVQEIIKR RLIAGIEKYK AKEGCIIVVQ
PFTLEILGLS CIPDFDLEKY YSFDEGYYKN QAISSLYEPG STFKPLVMAA GIQEGVITPN
SIFNEKGKIS IGEYNIKTWN DKYEGKITMT RVLEKSSNVG MVYVGEKLGN KKLLYYLKKY
GFGELTGIDL QGEVPGYLRA DDEWYPIDYA TATFGQGLVV SPIQMIRAFS TVINGGNLMT
PHVVKTLVGK MKTQKIEPQT ITRVVNEEVS QQIKEMLVST IENGETKYLK PKGYSIGGKT
GTAQIAIKGH YDASKTIASF IGFSPVETPQ FAILVVIKEP STSQWGSETA APLFFEIAKE
LIVYYNIAPE
//
