ID A0A1F7QMN0_9BACT Unreviewed; 595 AA.
AC A0A1F7QMN0;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=citrate synthase (unknown stereospecificity) {ECO:0000256|ARBA:ARBA00012972};
DE EC=2.3.3.16 {ECO:0000256|ARBA:ARBA00012972};
GN ORFNames=A3F37_00855 {ECO:0000313|EMBL:OGL30409.1};
OS Candidatus Saccharibacteria bacterium RIFCSPHIGHO2_12_FULL_41_12.
OC Bacteria; Candidatus Saccharibacteria.
OX NCBI_TaxID=1802138 {ECO:0000313|EMBL:OGL30409.1, ECO:0000313|Proteomes:UP000177946};
RN [1] {ECO:0000313|EMBL:OGL30409.1, ECO:0000313|Proteomes:UP000177946}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle.
CC {ECO:0000256|ARBA:ARBA00005163}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGL30409.1}.
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DR EMBL; MGCQ01000009; OGL30409.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F7QMN0; -.
DR STRING; 1802138.A3F37_00855; -.
DR UniPathway; UPA00223; -.
DR Proteomes; UP000177946; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0046912; F:acyltransferase activity, acyl groups converted into alkyl on transfer; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniPathway.
DR CDD; cd06100; CCL_ACL-C; 1.
DR Gene3D; 1.10.580.10; Citrate Synthase, domain 1; 1.
DR Gene3D; 1.10.230.10; Cytochrome P450-Terp, domain 2; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.50.261; Succinyl-CoA synthetase domains; 1.
DR InterPro; IPR016142; Citrate_synth-like_lrg_a-sub.
DR InterPro; IPR016143; Citrate_synth-like_sm_a-sub.
DR InterPro; IPR002020; Citrate_synthase.
DR InterPro; IPR036969; Citrate_synthase_sf.
DR InterPro; IPR005811; SUCC_ACL_C.
DR InterPro; IPR016102; Succinyl-CoA_synth-like.
DR PANTHER; PTHR23118; ATP-CITRATE SYNTHASE; 1.
DR PANTHER; PTHR23118:SF42; ATP-CITRATE SYNTHASE; 1.
DR Pfam; PF00285; Citrate_synt; 1.
DR Pfam; PF00549; Ligase_CoA; 1.
DR SUPFAM; SSF48256; Citrate synthase; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 176..300
FT /note="ATP-citrate synthase/succinyl-CoA ligase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00549"
SQ SEQUENCE 595 AA; 63964 MW; 0F2E72100E8413AE CRC64;
MNIDSLKQKK EIGAVVFGNH VGIIQSTLDF DYLSGKKRPS IRAVIGVQRN YLRYFWGSKE
IALPGHVSLD EMSKEAKEEV DLFAVAQSGR RATSACEEAL DQLPNVVGGM VFAEGVPERS
ALKLRDLAQK SGVFILGPAS VGFLVSGVCK IGAIGGTLAS QIAGSGITKA GLTAVVSTSG
GMTNEIINVI AGFGGSVSFA GAVGGERYPI LGPVELVELA INDDETKSIV FFGELGGRDE
YEIAQVYKNS GTTKPLICYI AGEVAESFES APQFGHAKAM AQSEQETASA KKQALSEAGA
KVADSFSHFE QLIKNSVAGE AKMNNNKIMN DDISDLENRK HATFVNNVSS DSGGDVTILG
KPLIDFIENK SLSQVALSMF LGKEPKSEEF ARFFDLSLRL LVDHGPQVSG AVNTMVTARA
GRDLGSGLAS GLLTIGPRFG GAINEAAKNW LEAVSKNENP QDFVERFASK KVYIAGIGHK
KYRVDSPDPR VTKLLSEFQS GEYTNFALEV QKITTTKKAQ LILNVDGLIA ALTLDMLEKE
EGYSPQQLSA LIDTEFFNAI FVYARSVGFI AHFLDQKRQD EGLFRLPDDQ ITSLT
//
