ID A0A1F7X7G4_9BACT Unreviewed; 693 AA.
AC A0A1F7X7G4;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=FtsK domain-containing protein {ECO:0000259|PROSITE:PS50901};
GN ORFNames=A2Y68_02235 {ECO:0000313|EMBL:OGM10235.1};
OS Candidatus Woesebacteria bacterium RBG_13_46_13.
OC Bacteria; Candidatus Woesebacteria.
OX NCBI_TaxID=1802479 {ECO:0000313|EMBL:OGM10235.1, ECO:0000313|Proteomes:UP000176778};
RN [1] {ECO:0000313|EMBL:OGM10235.1, ECO:0000313|Proteomes:UP000176778}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- SIMILARITY: Belongs to the FtsK/SpoIIIE/SftA family.
CC {ECO:0000256|ARBA:ARBA00006474}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGM10235.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MGFR01000001; OGM10235.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F7X7G4; -.
DR STRING; 1802479.A2Y68_02235; -.
DR Proteomes; UP000176778; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR CDD; cd01127; TrwB_TraG_TraD_VirD4; 1.
DR Gene3D; 3.30.980.40; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041027; FtsK_alpha.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR018541; Ftsk_gamma.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR22683:SF41; DNA TRANSLOCASE FTSK; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR Pfam; PF17854; FtsK_alpha; 1.
DR Pfam; PF09397; FtsK_gamma; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00843; Ftsk_gamma; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50901; FTSK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 54..77
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 89..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 120..142
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 352..539
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT REGION 173..197
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 369..376
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 693 AA; 74718 MW; 0517568AAAF3B5BA CRC64;
MSKRHRRSTK RAFNLRLKKG TVYSIVQVFF FALAGLILVS FSRQGLVLVR LNDLLISAFS
WTTFILPFLF LSFALLVSKI KNPLGQPNVV IGGLLFFVSI LTLGRAGAIG RMAWGGASSL
VTSIGAFIVL LGTTLVGLII LFNTSFEQVI ELASGIIAQA KKYILGEKGF SRQTSRGPMK
VSGGALPQAG ARPPQEVPGQ LEQKLVSNVP GEEKVWKYPS IELLSDVESG KANRGDIKGN
AATIEKTLES FGITARVVEV NLGPAVTQYA LEVALGTKLS KITSLERDLA LALSAPTGTI
RIEAPIPGRN LVGIELPNIS PEFVPLRRMM ESDVIRDNHS KLAVALGLDV SGKPIVTEIG
RMPHVLIAGQ TGSGKSVCIN AFLATILFRA APSEVKLIMV DPKRVELTHY NGIPHLLSPV
IVEPEKVISA LKWILAEMDR RYKLFAQAGA RNIDGYNEMS GFQALPYIVL FIDELADIML
FSPVEVEDAI TRIAQMSRAT GIHMVLATQR PSVDVITGLI KANIPCRIAF AVASQVDSRV
ILDTQGAEKL LGRGDMLYLP PEQAKPIRIQ GAFVSDKETN ALVAFLKNQG VTPQYTEEVT
SMPKGGGATV PGLTGEADDL FAEAVRVVCQ YERASASLLQ RRLSIGYARA ARIIDQLEAA
GVVSQAEGSK ARDVLVQNAE EFLASASQGS EPQ
//
