ID A0A1F7XA02_9BACT Unreviewed; 387 AA.
AC A0A1F7XA02;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE SubName: Full=GDP-mannose dehydrogenase {ECO:0000313|EMBL:OGM11198.1};
GN ORFNames=A2Z22_01790 {ECO:0000313|EMBL:OGM11198.1};
OS Candidatus Woesebacteria bacterium RBG_16_34_12.
OC Bacteria; Candidatus Woesebacteria.
OX NCBI_TaxID=1802480 {ECO:0000313|EMBL:OGM11198.1, ECO:0000313|Proteomes:UP000177053};
RN [1] {ECO:0000313|EMBL:OGM11198.1, ECO:0000313|Proteomes:UP000177053}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- SIMILARITY: Belongs to the UDP-glucose/GDP-mannose dehydrogenase
CC family. {ECO:0000256|PIRNR:PIRNR000124}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGM11198.1}.
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DR EMBL; MGFS01000024; OGM11198.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F7XA02; -.
DR Proteomes; UP000177053; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR017476; UDP-Glc/GDP-Man.
DR InterPro; IPR036220; UDP-Glc/GDP-Man_DH_C_sf.
DR InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer.
DR InterPro; IPR001732; UDP-Glc/GDP-Man_DH_N.
DR InterPro; IPR028359; UDP_ManNAc/GlcNAc_DH.
DR NCBIfam; TIGR03026; NDP-sugDHase; 1.
DR PANTHER; PTHR43491; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR PANTHER; PTHR43491:SF5; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR Pfam; PF00984; UDPG_MGDP_dh; 1.
DR Pfam; PF03721; UDPG_MGDP_dh_N; 1.
DR PIRSF; PIRSF500136; UDP_ManNAc_DH; 1.
DR PIRSF; PIRSF000124; UDPglc_GDPman_dh; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52413; UDP-glucose/GDP-mannose dehydrogenase C-terminal domain; 1.
PE 3: Inferred from homology;
FT DOMAIN 3..179
FT /note="UDP-glucose/GDP-mannose dehydrogenase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03721"
FT DOMAIN 201..291
FT /note="UDP-glucose/GDP-mannose dehydrogenase dimerisation"
FT /evidence="ECO:0000259|Pfam:PF00984"
SQ SEQUENCE 387 AA; 44033 MW; 628BD4365AA1BF07 CRC64;
MHKIAVIGLG KAGLPIAGVI ADSGFEVIGI DIDEKKCNQI NSGKNPIPDE KSLDELIKKH
GGKSLIAASK YEYAKDCNFF IIIVPLFIDE NHDPDFSIME NAFRNVGKIL KKGDCVVLET
TVPPQTTETI VRGWLEEESE LKFGEFYLAY SPERIMTGYS ISRLKEFPKV IGGVDEISGK
MAFEIYRKFI PNIHLVSTAR VAEFIKVIEG CYRDANIALA NELFKIADEI NVDFYEAREY
ANHQYCNIHL PSTGVGGHCI PYYPWFLIKE MEKIGKYDHC NLLRTSREIN DQMKDYWAEE
IILKCLQVDK SMKEIKICIN GITYRKGVKE LINSINLALV KLLIKKGLNV YVYDELFARE
EIVEMGLKFI DPEDADIVFD SFDLVIK
//
