ID A0A1F8A6U2_9EURO Unreviewed; 1067 AA.
AC A0A1F8A6U2;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Putative fumarylacetoacetate hydrolase {ECO:0000313|EMBL:OGM47472.1};
GN ORFNames=ABOM_002624 {ECO:0000313|EMBL:OGM47472.1};
OS Aspergillus bombycis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=109264 {ECO:0000313|EMBL:OGM47472.1, ECO:0000313|Proteomes:UP000179179};
RN [1] {ECO:0000313|EMBL:OGM47472.1, ECO:0000313|Proteomes:UP000179179}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 26010 {ECO:0000313|Proteomes:UP000179179};
RX PubMed=27664179;
RA Moore G.G., Mack B.M., Beltz S.B., Gilbert M.K.;
RT "Draft genome sequence of an aflatoxigenic Aspergillus species, A.
RT bombycis.";
RL Genome Biol. Evol. 0:0-0(2016).
CC -!- SIMILARITY: Belongs to the FAH family. {ECO:0000256|ARBA:ARBA00010211}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGM47472.1}.
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DR EMBL; LYCR01000023; OGM47472.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F8A6U2; -.
DR STRING; 109264.A0A1F8A6U2; -.
DR OrthoDB; 1430490at2759; -.
DR Proteomes; UP000179179; Unassembled WGS sequence.
DR GO; GO:0016810; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01299; Met_dep_hydrolase_A; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.90.850.10; Fumarylacetoacetase-like, C-terminal domain; 1.
DR Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR Gene3D; 2.30.40.10; Urease, subunit C, domain 1; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000073; AB_hydrolase_1.
DR InterPro; IPR006680; Amidohydro-rel.
DR InterPro; IPR011234; Fumarylacetoacetase-like_C.
DR InterPro; IPR036663; Fumarylacetoacetase_C_sf.
DR InterPro; IPR011059; Metal-dep_hydrolase_composite.
DR InterPro; IPR032466; Metal_Hydrolase.
DR PANTHER; PTHR11820; ACYLPYRUVASE; 1.
DR PANTHER; PTHR11820:SF115; FUMARYLACETOACETATE HYDROLASE; 1.
DR Pfam; PF00561; Abhydrolase_1; 1.
DR Pfam; PF01979; Amidohydro_1; 1.
DR Pfam; PF01557; FAA_hydrolase; 1.
DR PRINTS; PR00111; ABHYDROLASE.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF51338; Composite domain of metallo-dependent hydrolases; 1.
DR SUPFAM; SSF56529; FAH; 1.
DR SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:OGM47472.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000179179}.
FT DOMAIN 109..453
FT /note="Amidohydrolase-related"
FT /evidence="ECO:0000259|Pfam:PF01979"
FT DOMAIN 551..764
FT /note="Fumarylacetoacetase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01557"
FT DOMAIN 821..1052
FT /note="AB hydrolase-1"
FT /evidence="ECO:0000259|Pfam:PF00561"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1067 AA; 115873 MW; 4CE926FB37AC7BF9 CRC64;
MAPGILTNGF HDHPTPSSTL PTRRRPYPHD GLRFDPKLKP KSYRMTGTSP NSKILFLDVT
ILDSTGNDPY RGDVLIHGER IVSVGSVPDV EALRHDPKVR VIQGRGRTLM SGLGDAHTHW
TWNNIALELL GDIGVEEHTL ITARSALCYL DSGYTMCYGA ASAKDRLDCV VRDAINRGTL
PGPRLLANGR EIAKREGELA AGITAFAEGP LEMREVIRHH AKIGVDQIKL SMSGEAITET
VSAEECFFTD EETAACVDEA HRNGIRVCSH ARARDSVIQC ARHGVDVIYH ASYTDEEGMQ
MLEKVKDRVV VAPALNWLYA TVYEAEPFGY SMEKAEQVGY RKELETAIKA LKEMHKRGIT
VLPGGDYGFA WCPHGTYARD LEHFVKLLDF TPMESIVAAT AGIAKLFMQD DELGKILPGY
YADCILVDGD PLKDIAVLQD HSKLDVIMIN GRIHKAQPAE FLSMATVPPS LQEEKSYFNF
VVFEDDLGRS RIGHLDLGDS TIQPLTMASG SPLASLSQAI ELGDGGVVRA AEPPFPLSSV
KLLPPLADRD VLCIGENYRK HIKEYQESGY AAAGNKVTDS PKVPTVFTKR STSITASGTD
IYPHPGFTET MDYEGELGVI IGKAGFSIKE KDAMDYVWGY TIINDLSARE RQRDHRQYFM
GKSPDTFCPM GPVAVPAAAL PGEIRVQTHV NGEKRQDGTT ADLIFSIPKL IETVSSGITL
QPGDVIATGT PHGVGVGHHP PKFLKPGDLV EVSVTGLGKL SNRIADPGSK NPTIDRVLQK
PSSIPTYNLD RTWGGVGLTK VGPDHYINVR ELGSQSPDAE TIVFIHGLGA NLEYYAPLIQ
AAGLEKDYRV ILYDLEGHGA TPTRASSTAT LQTFARDLDL LFAAKSIRSA TLVGWSLGGL
IAMFFAEKHP SRVSTLVLLG PGPTPFPEPA VEVFTKRAAV VREKGMEASG VASAVATAAT
SSVTQSRPLA LSAVRQSLLS THPEGYAKGC IALARSRGTV ITVENLRMST LIVAGQEDAI
SPVKLAQGYR SKIPHSQVEL LKDVGHWHVF EDLEGTAQAI KRFLGRS
//
