ID A0A1F8B4W9_9BACT Unreviewed; 583 AA.
AC A0A1F8B4W9;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=DNA ligase (ATP) {ECO:0000256|ARBA:ARBA00012727};
DE EC=6.5.1.1 {ECO:0000256|ARBA:ARBA00012727};
GN ORFNames=A3A75_05410 {ECO:0000313|EMBL:OGM59074.1};
OS Candidatus Woesebacteria bacterium RIFCSPLOWO2_01_FULL_39_10.
OC Bacteria; Candidatus Woesebacteria.
OX NCBI_TaxID=1802516 {ECO:0000313|EMBL:OGM59074.1, ECO:0000313|Proteomes:UP000179018};
RN [1] {ECO:0000313|EMBL:OGM59074.1, ECO:0000313|Proteomes:UP000179018}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-
CC (deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP +
CC diphosphate.; EC=6.5.1.1; Evidence={ECO:0000256|ARBA:ARBA00034003};
CC -!- SIMILARITY: Belongs to the ATP-dependent DNA ligase family.
CC {ECO:0000256|ARBA:ARBA00007572, ECO:0000256|RuleBase:RU004196}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGM59074.1}.
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DR EMBL; MGHC01000027; OGM59074.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F8B4W9; -.
DR STRING; 1802516.A3A75_05410; -.
DR Proteomes; UP000179018; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR GO; GO:0071897; P:DNA biosynthetic process; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 1.10.3260.10; DNA ligase, ATP-dependent, N-terminal domain; 1.
DR Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR000977; DNA_ligase_ATP-dep.
DR InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR InterPro; IPR012308; DNA_ligase_ATP-dep_N.
DR InterPro; IPR036599; DNA_ligase_N_sf.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR NCBIfam; TIGR00574; dnl1; 1.
DR PANTHER; PTHR45674; DNA LIGASE 1/3 FAMILY MEMBER; 1.
DR PANTHER; PTHR45674:SF9; DNA LIGASE 3; 1.
DR Pfam; PF04679; DNA_ligase_A_C; 1.
DR Pfam; PF01068; DNA_ligase_A_M; 1.
DR Pfam; PF04675; DNA_ligase_A_N; 1.
DR SUPFAM; SSF117018; ATP-dependent DNA ligase DNA-binding domain; 1.
DR SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 338..474
FT /note="ATP-dependent DNA ligase family profile"
FT /evidence="ECO:0000259|PROSITE:PS50160"
SQ SEQUENCE 583 AA; 66303 MW; D90A8EF5206A69E8 CRC64;
MKFRELSLYL QQLEKTASRI EITKILAEFF RKADAAEIDK ATYLLLGKLA PNYKGIVFNI
KDRMMIRILA KAYGKDQRVV LSKYKQKGDL GGVAQDLASG RGGNISVTEV YEKLLKVAEE
HGEDSQERKV LGLAQILSLL DPLSSRYVTR IPLGRLRLGF SDKTILDALS WMEKGDKSAK
NALERAYEVL PDVGLLAKEV KLKGIERATK DASPMLGVPI MPMLAQRLKS PSEMIEKMGE
VAVEPKFDGL RISIHFKSKG FAKDVTEGLK SNNDKVKAFT RNMNETSWMF PELKLAESFI
KADEVILDSE AVGVDETRKI LANFQQTMTR RRKHEIEKIS AQIPIKFYVF DILYKDGKSL
IDLKYLERRK MLEKTVKDGR LFEVVAYQIT DKPEEIKFQN SQKRKMGFEG IIIKRLSSEY
VPGRTGWRWV KMKEAEESVG KMADTVDCVV MGYTRGKGKR VSFGLGQFLV GVRDNEEIKT
VTKVGTGLTD EQFRELKKRL SGLEVKEKPK NYEVNKLLEP DFWVVPEVVV EIAADEVTKS
PTHSSGYALR FPRLVRFRDD KDPTGATTVK ELKKLLDMQK FDI
//
