ID A0A1F8E3B1_9BACT Unreviewed; 552 AA.
AC A0A1F8E3B1;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Metallo-beta-lactamase domain-containing protein {ECO:0000259|SMART:SM00849};
GN ORFNames=A2610_02490 {ECO:0000313|EMBL:OGM95353.1};
OS Candidatus Wolfebacteria bacterium RIFOXYD1_FULL_48_65.
OC Bacteria; Candidatus Wolfebacteria.
OX NCBI_TaxID=1802561 {ECO:0000313|EMBL:OGM95353.1, ECO:0000313|Proteomes:UP000179057};
RN [1] {ECO:0000313|EMBL:OGM95353.1, ECO:0000313|Proteomes:UP000179057}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGM95353.1}.
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DR EMBL; MGIV01000008; OGM95353.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F8E3B1; -.
DR Proteomes; UP000179057; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR CDD; cd07714; RNaseJ_MBL-fold; 1.
DR Gene3D; 3.10.20.580; -; 1.
DR Gene3D; 3.40.50.10710; Metallo-hydrolase/oxidoreductase; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR InterPro; IPR011108; RMMBL.
DR InterPro; IPR004613; RNase_J.
DR InterPro; IPR042173; RNase_J_2.
DR InterPro; IPR041636; RNase_J_C.
DR NCBIfam; TIGR00649; MG423; 1.
DR PANTHER; PTHR43694; RIBONUCLEASE J; 1.
DR PANTHER; PTHR43694:SF1; RIBONUCLEASE J; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR Pfam; PF07521; RMMBL; 1.
DR Pfam; PF17770; RNase_J_C; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 14..210
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 552 AA; 61700 MW; 569DA579A92284F9 CRC64;
MVRFCGLGGL EEIGRNMSFF EYKDEIVIFD AGLEFAGEEN PGVDYIIPNT TYLEQNKHKI
RGIVVTHAHY DHIGAIPHIM EKLGNPTIYT TPLAREIIKK RQTDYPNTPP LDIEIVKNRD
VIKVSDNFTL EFFNIIHSIP DSISIMLKTP VGNFVYATDV KVEYDAKGVE YGLDEFRRVG
EQGIHGLFLE STNAEVPGKS LSSELIMDNI EDIFLKTKGR MVIAMFASML TRVGEVITLA
EKHGKKIAFS GLSMKTNVQI AQNLGYIKIK PGTIIQLADI HKYKDDQIVI LSTGAQGESN
ASLMKIATGE NRSFQTRPGD TIMFSSSIIP GNERAVQTLK DSLARQGAHI YHSKNSDIYS
SGHATADELK AIIKAVKPKY YVPIHGYYFM RSTNALLAQE CGVLKENTIV ADNGLVVEFS
KTGFQVDFDH QLPAHYVMVD GLGVGDVGEI VMRDRKMLAE EGMVVIVATL DKKTGTVIKS
PDIVSRGFIY LKENVNIVED MRKKIKGILA QMPAHKEVEM DYLKGLIRDQ IGQFLYTKTK
RRPMILPVII YV
//
