ID A0A1F8FHA7_9BACT Unreviewed; 506 AA.
AC A0A1F8FHA7;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 12.
DE RecName: Full=Penicillin-binding protein transpeptidase domain-containing protein {ECO:0000259|Pfam:PF00905};
GN ORFNames=A3C71_01920 {ECO:0000313|EMBL:OGN12507.1};
OS Candidatus Yanofskybacteria bacterium RIFCSPHIGHO2_02_FULL_43_15c.
OC Bacteria; Candidatus Yanofskybacteria.
OX NCBI_TaxID=1802679 {ECO:0000313|EMBL:OGN12507.1, ECO:0000313|Proteomes:UP000178197};
RN [1] {ECO:0000313|EMBL:OGN12507.1, ECO:0000313|Proteomes:UP000178197}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGN12507.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MGJT01000017; OGN12507.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F8FHA7; -.
DR Proteomes; UP000178197; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 188..480
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 506 AA; 56147 MW; 0992D021D23830C8 CRC64;
MLSKWRINLF TVVLFGAVGL IFYRLFYLTY LQHDVLSKIA EGQYQNQQEN SVRRGHIYIR
DLSTGEKQLV ALQKSFPYVF SKKDGRFKIV DKNPPPAEVE RLRQESGQET SLGYEDGRYY
PEGSFLAQVL GFLGFDENRR VGQYGLEAYY DETIRKENDL ILTIDKNIQS FAEKELDYLL
DKWRPVSGTV IVQDPQTGAI LAMAGSPSFD PNNYGNYPLG NFVNKAVQEA FEPGSSFKPI
TMSGALDKKK VTPETTYFDT GEVEIAGYKI KNFNEKSFGT QTMSQVLEKS LNTGAMFVES
QLGDDDFLNY VINFGFGQAT GIDLAGEAAG DTSNLYSKRK INFLTASFGQ GISVTPIQLV
NAYSAIANGG KLMRPYVVKK VVKPSGETKE TKPEVIGTPI SEKTSAQVKA MLVGVVEKGF
DKAKVKGYDV AAKTGTAQIA SPKGGYSEEF IHDMVGFAPA FSPRFVVLIK MDKPQGIRFA
ADSLSPSLGN ITRFLLNYFQ IPPTRQ
//
