ID A0A1F8LMX6_9CHLR Unreviewed; 358 AA.
AC A0A1F8LMX6;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Threonine aldolase {ECO:0000313|EMBL:OGN87737.1};
GN ORFNames=A2X23_07860 {ECO:0000313|EMBL:OGN87737.1};
OS Chloroflexi bacterium GWC2_73_18.
OC Bacteria; Chloroflexota.
OX NCBI_TaxID=1797616 {ECO:0000313|EMBL:OGN87737.1, ECO:0000313|Proteomes:UP000176763};
RN [1] {ECO:0000313|EMBL:OGN87737.1, ECO:0000313|Proteomes:UP000176763}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the threonine aldolase family.
CC {ECO:0000256|ARBA:ARBA00006966}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGN87737.1}.
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DR EMBL; MGMJ01000031; OGN87737.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F8LMX6; -.
DR STRING; 1797616.A2X23_07860; -.
DR Proteomes; UP000176763; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:InterPro.
DR GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR001597; ArAA_b-elim_lyase/Thr_aldolase.
DR InterPro; IPR023603; Low_specificity_L-TA-like.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR NCBIfam; NF041359; GntG_guanitoxin; 1.
DR PANTHER; PTHR48097:SF9; L-THREONINE ALDOLASE; 1.
DR PANTHER; PTHR48097; L-THREONINE ALDOLASE-RELATED; 1.
DR Pfam; PF01212; Beta_elim_lyase; 1.
DR PIRSF; PIRSF017617; Thr_aldolase; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
FT DOMAIN 9..283
FT /note="Aromatic amino acid beta-eliminating lyase/threonine
FT aldolase"
FT /evidence="ECO:0000259|Pfam:PF01212"
FT MOD_RES 207
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR017617-1"
SQ SEQUENCE 358 AA; 37747 MW; 2F0BF73EA09687A6 CRC64;
MPSPTGLIDL RSDTVTHPTP EMRRAMAEAE VGDDVFGDDP TVIRLEERAA ELLGKEAALF
VSSGTQGNLV SLMAHLARGT EIIAETESHT VMDEAAGHAV VVGASARTIP ARPDGTMDPA
AIAAAFRDPS DPHEPITGLV ALENTHAHSM GQPLTATYTA EVAAIAHERG VPLHVDGARL
FNAQVALGVP ARELVEAADS VTFCLSKGLA CPVGSVVVGR RDFIWRARRA RKLLGGGMRQ
VGVLAAPGLI ALRDGPTGMI ERLADDHANA RRLAEALAAM PGVWGPEPGI PLDPARARTN
FVVFRVAPGR RAAFLESLRG EGILMVEYPH ETIRAVTHYG IEAADVERTI AAVGRAAP
//
