ID A0A1F8M6Z0_9CHLR Unreviewed; 685 AA.
AC A0A1F8M6Z0;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=A2Z71_09420 {ECO:0000313|EMBL:OGN94377.1};
OS Chloroflexi bacterium RBG_13_50_21.
OC Bacteria; Chloroflexota.
OX NCBI_TaxID=1797623 {ECO:0000313|EMBL:OGN94377.1, ECO:0000313|Proteomes:UP000177581};
RN [1] {ECO:0000313|EMBL:OGN94377.1, ECO:0000313|Proteomes:UP000177581}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGN94377.1}.
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DR EMBL; MGMQ01000113; OGN94377.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F8M6Z0; -.
DR STRING; 1797623.A2Z71_09420; -.
DR Proteomes; UP000177581; Unassembled WGS sequence.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR43304:SF1; PAC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43304; PHYTOCHROME-LIKE PROTEIN CPH1; 1.
DR Pfam; PF13185; GAF_2; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF13426; PAS_9; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT DOMAIN 31..105
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 108..160
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 322..368
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 462..676
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 685 AA; 77834 MW; F37F7302EAE047DE CRC64;
MPETTQPIDG GRSANGRKKG GKEPKSIEST MEVRYRALVE QVPAVIYTDS AENIFETLYI
SPQLKSLTGY DPEEWLTDIN LWNRIIFPED QERVIEEYTR TYTAMVPSVS EYRITTRDGR
IIWVSDETRL VRDRKGKPLF WQGVMVDITA RKRAEQIQGI TYRISHAVIS TTSLEELYTS
IHSILGELIP IQNFYIALYD AADDLISFPY YIDQYDEPPT PGKPEHGLTE YVMRTKKPLW
ASQKVFTQLE EQGEVEIIGT DSIEWVGVPL MVGERLTGVM VTQNYTEGVA YAQEHVDLME
FASTQVAMAI ERKRDQQRIA DALEYNKTLI NSSSLGIGTY DTSGECILAN ESFLKILGTT
RDQVLGENYN QSKIWKKSGM LDAAREALAS GNETRKEIHT KSAGGKEIWL DCRFTPFTSH
SEPHLLLSVD DITISKRAEV DLKIYAARLE QSNRDLQEFA YIASHDLQEP LRKVLAFGDR
LASKYGDLLD ETGRDYLKRM RDASQRMQTL INDLLSFSRV TTRAQPFDVV DLNSLAQEVV
SDLEYQIDRT HGYVVIENLP VIEADPTQMH QLLQNLITNG LKFHQEDTPP TVLVTAQILD
SKCQIQVKDN GIGFEEQYLD RIFKPFQRLH SRQEYEGSGM GLAICRRIVE RHSGEITASS
KPGVGSTFTV TLPIFQTIGE RAYVQ
//
