ID A0A1F8MZ08_9CHLR Unreviewed; 457 AA.
AC A0A1F8MZ08;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 28-JUN-2023, entry version 14.
DE RecName: Full=Major facilitator superfamily (MFS) profile domain-containing protein {ECO:0000259|PROSITE:PS50850};
GN ORFNames=A2Y72_02400 {ECO:0000313|EMBL:OGO03868.1};
OS Chloroflexi bacterium RBG_13_53_26.
OC Bacteria; Chloroflexota.
OX NCBI_TaxID=1797629 {ECO:0000313|EMBL:OGO03868.1, ECO:0000313|Proteomes:UP000180304};
RN [1] {ECO:0000313|EMBL:OGO03868.1, ECO:0000313|Proteomes:UP000180304}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGO03868.1}.
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DR EMBL; MGMW01000004; OGO03868.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F8MZ08; -.
DR Proteomes; UP000180304; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR024989; MFS_assoc_dom.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR23526; INTEGRAL MEMBRANE TRANSPORT PROTEIN-RELATED; 1.
DR PANTHER; PTHR23526:SF2; MAJOR FACILITATOR SUPERFAMILY MFS_1; 1.
DR Pfam; PF12832; MFS_1_like; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 55..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 88..111
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 117..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 160..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 185..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 236..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 269..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 302..318
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 324..349
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 361..383
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 389..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..417
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 457 AA; 50540 MW; B53D35FC50EDC7EB CRC64;
MNFPHFSPDV PSKLSEGQVK KSLRNSIFDG SAHSVMLGLT QNYITPYALT MKASIQQIGL
LTSVANFTMA AAQFVAPTLS ERIGSRKGFI LPMVLIHALM WLPILAIPYL FQTHQVWWLI
LFMTLSTAFG SAVDPAWGSM MADLVPRQMR GRYFGLRNRI TAFVSMALSY AAGGILQLLT
GNTNLAFTII FIGAIASRLV SLYFLSKMYE PLSPATEQRG HESTLKLARG LFSTNIGMFI
MLCALMTFSA AVAGPFFSPY MLNDLNMSYI VYTALNSVTG LATVGFMTWW GKRIDRAGSI
KVLKITSLLV PFVPLGWLPS HSLWWLAIMQ IFSGFAWAGF QLSAGVFIFD AAPPRNRTRY
IALYNSLVYL GASVGALVGG VVTPLLPPIL GSSFLSIFAV SGAARLAVAL FFRPRIKEVR
KVPHIEASEL LFSDSQRPWI DRAYGYVVAY FRRRKID
//
