ID A0A1F8NRM0_9CHLR Unreviewed; 512 AA.
AC A0A1F8NRM0;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=DNA-directed DNA polymerase {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=A2Y93_17260 {ECO:0000313|EMBL:OGO13536.1};
OS Chloroflexi bacterium RBG_13_68_17.
OC Bacteria; Chloroflexota.
OX NCBI_TaxID=1797638 {ECO:0000313|EMBL:OGO13536.1, ECO:0000313|Proteomes:UP000178211};
RN [1] {ECO:0000313|EMBL:OGO13536.1, ECO:0000313|Proteomes:UP000178211}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGO13536.1}.
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DR EMBL; MGNF01000105; OGO13536.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F8NRM0; -.
DR Proteomes; UP000178211; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR CDD; cd00141; NT_POLXc; 1.
DR CDD; cd07436; PHP_PolX; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR Gene3D; 3.30.210.10; DNA polymerase, thumb domain; 1.
DR Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR InterPro; IPR002054; DNA-dir_DNA_pol_X.
DR InterPro; IPR037160; DNA_Pol_thumb_sf.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR004013; PHP_dom.
DR InterPro; IPR003141; Pol/His_phosphatase_N.
DR InterPro; IPR016195; Pol/histidinol_Pase-like.
DR InterPro; IPR029398; PolB_thumb.
DR InterPro; IPR047967; PolX_PHP.
DR PANTHER; PTHR36928; PHOSPHATASE YCDX-RELATED; 1.
DR PANTHER; PTHR36928:SF1; PHOSPHATASE YCDX-RELATED; 1.
DR Pfam; PF14791; DNA_pol_B_thumb; 1.
DR Pfam; PF14520; HHH_5; 1.
DR Pfam; PF02811; PHP; 1.
DR SMART; SM00481; POLIIIAc; 1.
DR SMART; SM00483; POLXc; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF89550; PHP domain-like; 1.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 1.
PE 4: Predicted;
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1..253
FT /note="DNA-directed DNA polymerase X"
FT /evidence="ECO:0000259|SMART:SM00483"
FT DOMAIN 277..357
FT /note="Polymerase/histidinol phosphatase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00481"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:OGO13536.1"
SQ SEQUENCE 512 AA; 56025 MW; 43F88E4EFA973893 CRC64;
IATKIDELLR TGKLEFAEKL AGEVPPGLVD VLKVEGVGPR KAARFWKDLG ITTLADLEQA
ARAGKLRDMP GMGARSEERI LKGIESLRRR DVGRVSIGRA RPVALALLAE LERMPGVRKA
EMAGSLRRWR ETVGDIDLLV AAADSKEVIR RFAGLPRVAR VLGQGETKVS VELQDGLRAQ
VWVHPPERFG SALQYATGSQ AHNVRLRELA QQRGLSLSEH GFKKAGGGEI LCGSEEEVYR
RLGLPWIPPE LREDRGEIQA AQRGEVPALV TLADLTAELH AHSTWSDGQN SIEEMARAAQ
SLGLKALVIS DHSQSLGVAN GLTVERLRRQ AKEIESVQRR IGGDLRLLRG TEVEIRADGA
LDYPDEILRQ LDVVTASVHT SLRQSREKMT ARLLGAIRNP HVDVIGHPTG RMVEGRDPAE
VDIEAVFLAA LQAGVALEIN AHPARLDLDE GNARRAVELG CLLAINVDAH SPSDFALREY
GVGIARRGWV PPGAVVNTWP IDRLDAWLHR WG
//
