ID A0A1F8NW11_9CHLR Unreviewed; 344 AA.
AC A0A1F8NW11;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=Manganese transport regulator {ECO:0000256|ARBA:ARBA00032593};
GN ORFNames=A2Z14_17925 {ECO:0000313|EMBL:OGO15106.1};
OS Chloroflexi bacterium RBG_16_48_8.
OC Bacteria; Chloroflexota.
OX NCBI_TaxID=1797641 {ECO:0000313|EMBL:OGO15106.1, ECO:0000313|Proteomes:UP000177106};
RN [1] {ECO:0000313|EMBL:OGO15106.1, ECO:0000313|Proteomes:UP000177106}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGO15106.1}.
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DR EMBL; MGNI01000216; OGO15106.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F8NW11; -.
DR STRING; 1797641.A2Z14_17925; -.
DR Proteomes; UP000177106; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0046914; F:transition metal ion binding; IEA:InterPro.
DR Gene3D; 2.30.30.90; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR007167; Fe-transptr_FeoA.
DR InterPro; IPR001367; Fe_dep_repressor.
DR InterPro; IPR036421; Fe_dep_repressor_sf.
DR InterPro; IPR038157; FeoA_core_dom.
DR InterPro; IPR022689; Iron_dep_repressor.
DR InterPro; IPR008988; Transcriptional_repressor_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR33238; IRON (METAL) DEPENDENT REPRESSOR, DTXR FAMILY; 1.
DR PANTHER; PTHR33238:SF7; TRANSCRIPTIONAL REGULATOR MNTR; 1.
DR Pfam; PF02742; Fe_dep_repr_C; 1.
DR Pfam; PF04023; FeoA; 1.
DR SMART; SM00899; FeoA; 2.
DR SMART; SM00529; HTH_DTXR; 1.
DR SUPFAM; SSF50037; C-terminal domain of transcriptional repressors; 1.
DR SUPFAM; SSF47979; Iron-dependent repressor protein, dimerization domain; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004}; Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..22
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 180..251
FT /note="Ferrous iron transporter FeoA"
FT /evidence="ECO:0000259|SMART:SM00899"
FT DOMAIN 264..338
FT /note="Ferrous iron transporter FeoA"
FT /evidence="ECO:0000259|SMART:SM00899"
SQ SEQUENCE 344 AA; 37816 MW; 7E63AA873420AAAD CRC64;
MPEPLLALLG GALLVLLSFW FFRPERGILA RWQRSLHITE RMLVEDALKH IHNREMAGDL
PTINSIAGTL QISDKEAAEL VAKIEAAELV EQEGSKLHLT SGGRESALHI LRAHRLWERY
LADSTGFSES EWHSQADLYE HLLSSADTDA LSAQLGHPIY DPHGDPIPSS NGELIPIAGT
PLTAANLEAP LRIVHIEDEP QTVYDQLVAE GLHPGMIVNV IETSPKRVRF WAEGDEHILA
PIVASNISVA PIPEEKECET LPCEHLSDLK SGEEAVVSGI SLACRGFERR RLLDLGILPG
TVIRAEFASP SGDPTAYRIR DALIALRDEQ AKLVQITRPE KEAA
//
