ID A0A1F8NX21_9CHLR Unreviewed; 447 AA.
AC A0A1F8NX21;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=4Fe-4S domain-containing protein {ECO:0000259|PROSITE:PS51656};
GN ORFNames=A2Y93_07935 {ECO:0000313|EMBL:OGO15443.1};
OS Chloroflexi bacterium RBG_13_68_17.
OC Bacteria; Chloroflexota.
OX NCBI_TaxID=1797638 {ECO:0000313|EMBL:OGO15443.1, ECO:0000313|Proteomes:UP000178211};
RN [1] {ECO:0000313|EMBL:OGO15443.1, ECO:0000313|Proteomes:UP000178211}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGO15443.1}.
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DR EMBL; MGNF01000043; OGO15443.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F8NX21; -.
DR Proteomes; UP000178211; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0008168; F:methyltransferase activity; IEA:InterPro.
DR GO; GO:0046356; P:acetyl-CoA catabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.11600; -; 1.
DR Gene3D; 3.20.20.20; Dihydropteroate synthase-like; 1.
DR InterPro; IPR007202; 4Fe-4S_dom.
DR InterPro; IPR016041; Ac-CoA_synth_d_su_TIM-brl.
DR InterPro; IPR016218; AcylCoA_decarb/synth_gsu.
DR InterPro; IPR011005; Dihydropteroate_synth-like_sf.
DR PANTHER; PTHR36214; -; 1.
DR PANTHER; PTHR36214:SF3; ACETYL-COA DECARBONYLASE_SYNTHASE COMPLEX SUBUNIT GAMMA; 1.
DR Pfam; PF03599; CdhD; 1.
DR Pfam; PF04060; FeS; 1.
DR PIRSF; PIRSF000376; AcCoA_decarb_gamma; 1.
DR SUPFAM; SSF51717; Dihydropteroate synthetase-like; 1.
DR PROSITE; PS51656; 4FE4S; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485, ECO:0000256|PIRSR:PIRSR000376-2};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR000376-2};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014, ECO:0000256|PIRSR:PIRSR000376-
KW 2};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|PIRSR:PIRSR000376-2}.
FT DOMAIN 1..59
FT /note="4Fe-4S"
FT /evidence="ECO:0000259|PROSITE:PS51656"
FT BINDING 17
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /evidence="ECO:0000256|PIRSR:PIRSR000376-2"
FT BINDING 20
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /evidence="ECO:0000256|PIRSR:PIRSR000376-2"
FT BINDING 25
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /evidence="ECO:0000256|PIRSR:PIRSR000376-2"
FT BINDING 42
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /evidence="ECO:0000256|PIRSR:PIRSR000376-2"
FT BINDING 340
FT /ligand="5-methoxybenzimidazolylcob(I)amide"
FT /ligand_id="ChEBI:CHEBI:157765"
FT /evidence="ECO:0000256|PIRSR:PIRSR000376-1"
FT BINDING 346
FT /ligand="5-methoxybenzimidazolylcob(I)amide"
FT /ligand_id="ChEBI:CHEBI:157765"
FT /evidence="ECO:0000256|PIRSR:PIRSR000376-1"
FT BINDING 370..373
FT /ligand="5-methoxybenzimidazolylcob(I)amide"
FT /ligand_id="ChEBI:CHEBI:157765"
FT /evidence="ECO:0000256|PIRSR:PIRSR000376-1"
FT BINDING 434
FT /ligand="5-methoxybenzimidazolylcob(I)amide"
FT /ligand_id="ChEBI:CHEBI:157765"
FT /evidence="ECO:0000256|PIRSR:PIRSR000376-1"
SQ SEQUENCE 447 AA; 48043 MW; 65E8FD745FE1D3AA CRC64;
MPLTGLEIYK LLPQTNCKEC GFPTCLAFAM KLAAKQAELK ACPYVSEESK AKLEAASSPP
IRLVSLSGEA GKLEVGNETV MFRHEKTFYH LPGLFWHLRD TDGPEALKAK VAPADAYRVD
YVGIKLGLDG FAVEAASGDP AAFKAAVQAV RAVSKKPLIL MASTPELAKA GLEAAAGTTP
LLYAATPENW QAMAEVAKAA KVPLAARAPD LGQLADLTQS LTGAGIENLV VDPVVTGYRD
SLEKLTSIRR LALKKAFRPL GFPVITFPGQ AKDADETLLA AEHIAKYGAL VVLDTFDPAS
LYPLLVLRQN IYTDPQKPIQ VQPGLYEINA PNDKSPVLVT TNFSITYFAV SNEVEGSGWP
AWLIVCDAEG MSVLTAWAAG KFDAERITKS VKLSAIKDKI SHQRVIIPGA VAVLSGELEE
ELQGWQIMVG PREAVDIGTY LKAMWPN
//
