ID A0A1F8NZX9_9CHLR Unreviewed; 1026 AA.
AC A0A1F8NZX9;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=A2Z14_19510 {ECO:0000313|EMBL:OGO16475.1};
OS Chloroflexi bacterium RBG_16_48_8.
OC Bacteria; Chloroflexota.
OX NCBI_TaxID=1797641 {ECO:0000313|EMBL:OGO16475.1, ECO:0000313|Proteomes:UP000177106};
RN [1] {ECO:0000313|EMBL:OGO16475.1, ECO:0000313|Proteomes:UP000177106}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGO16475.1}.
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DR EMBL; MGNI01000171; OGO16475.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F8NZX9; -.
DR STRING; 1797641.A2Z14_19510; -.
DR Proteomes; UP000177106; Unassembled WGS sequence.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 3.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR43711:SF32; DRUG SENSORY PROTEIN A; 1.
DR PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF13185; GAF_2; 2.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF13426; PAS_9; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 2.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 3.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 2.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT DOMAIN 547..617
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 622..674
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 675..731
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 746..800
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 804..1026
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 523..550
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1026 AA; 114836 MW; 489C8284AB016942 CRC64;
MVQLKHKETE VYPKSVWAEA MRATVAVARR SLKGEDALLR AVSDELQRLE MTGFILLLCE
DGLLELRATP SVLEQRLKEL TGLDVRGLRF DPHKVDVYQR VLKDLESFFE SSHKPILEQV
LPKETRPLTG KLIEALGVHP IIYAPLFVEE KVLGVMNVSA EWFTVEDVPM VSSLADHIAI
SLSHMRTSLE FQNILKRERL RTRVAEVIAN SWDLDQILDR ILHMVVEAVR AEAGSIALVE
PGAQLLRLYH LYALPQALGL KQVPRNQGLA WKMIEDGKPV IHNNYAQHPD ALQEWVDAGV
QAVMSAPLIT GDEIIGTMAI FLLESGREFD QNHLEILKDI SHLAAGVINN VQLFNEATRY
AEEAEALRRG SIAISSSLDY HTVLTEITEQ AKALLRADGS RVHLLDQESG LLRCVIALHP
HAEEVMQIEL KPGEGLSGHV LLSSEPLLVN RPTDHPHSIQ VPGTPQDEAE VLAIAPMKIR
KRTMGVMTVQ RDGYTRPFSE PDLRLLSAFA SQAAVAIENA HLYGQIESQA QRLEDEVKAR
TRELTFSEAR YRSLVETSLT GIYQLDKNAK IAYVNDQLAE MLELEPEEII GRSVVDFLAP
EYRESVLKWA VARLNGEEPL TEIVEVKLLS WSGRHIPVIL AAGVITNETG IPESISGLVL
DISTQKRLEA ALRTERDRLE IILRNVGDAV VVTDPSGIIE FVNPAWEHLN GYHAQEALGK
NANLVKSDEQ DPDFYFQMWD TILAGRVWRG EVINRRKDGS TYEAALTITP VKNESRQIVN
FVGVQHDISM LKELDRLKSQ FVSDVSHELR TPLTNIRLYL ELLTQTEYDQ RAGRYMETLS
RESERLSSLI EDLLSLSRLE ADSAPLNKEP VDINRMLSAL TQDREKLATQ YGLELRLECE
AKLPLVMGDA LLLSQLFTNL LTNALNYTPE GGYILLRTRS QSSGEMIWVV AEVEDTGYGI
PPMEHSLIFR RFFRGQASKP AAVPGTGLGL AICKEITERH GGKIMVESDG ILGHGSRFTV
WLPVSG
//
