ID A0A1F8P4W5_9CHLR Unreviewed; 365 AA.
AC A0A1F8P4W5;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Mycofactocin radical SAM maturase {ECO:0000313|EMBL:OGO17901.1};
GN ORFNames=A2Z15_00850 {ECO:0000313|EMBL:OGO17901.1};
OS Chloroflexi bacterium RBG_16_50_11.
OC Bacteria; Chloroflexota.
OX NCBI_TaxID=1797642 {ECO:0000313|EMBL:OGO17901.1, ECO:0000313|Proteomes:UP000179337};
RN [1] {ECO:0000313|EMBL:OGO17901.1, ECO:0000313|Proteomes:UP000179337}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGO17901.1}.
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DR EMBL; MGNJ01000107; OGO17901.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F8P4W5; -.
DR Proteomes; UP000179337; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR023885; 4Fe4S-binding_SPASM_dom.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR023913; MftC.
DR InterPro; IPR017200; PqqE-like.
DR InterPro; IPR007197; rSAM.
DR NCBIfam; TIGR03962; mycofact_rSAM; 1.
DR NCBIfam; TIGR04085; rSAM_more_4Fe4S; 1.
DR PANTHER; PTHR11228:SF7; PQQA PEPTIDE CYCLASE; 1.
DR PANTHER; PTHR11228; RADICAL SAM DOMAIN PROTEIN; 1.
DR Pfam; PF13353; Fer4_12; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR PIRSF; PIRSF037420; PQQ_syn_pqqE; 2.
DR SFLD; SFLDG01386; main_SPASM_domain-containing; 1.
DR SFLD; SFLDG01067; SPASM/twitch_domain_containing; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 8..237
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 365 AA; 40265 MW; F6A0E92528DDA307 CRC64;
MKYADWPLSA PVNITWEITH RCNLRCVHCL SGSSVASESE LNFNECRGIV DQLAELKVFE
INFGGGEPLL KDYFLPLLRY IHQKGIVTCI STNGTVLTDE AIACFTDNPL VNVQVSLDGA
TPEVNDAIRG RGTFRCIIGG IERLAGKNIP LSINTVVTSL NYMQLKQLKE LAAAYGANLR
VSRFRPSGRA RASWEALRLN SLQLRELADW LNSEPGVLTG DSFFSISQDG RRQLGLDMCG
ACKMTACIDP IGNVYPCAFM QDTPFCGGNL REKMTRHSRP HAALRVNSSG NPGEGFKDIW
ENAAAFKYFR QLEPEACHSC SRFDKCRGGC PSVAYFVSQD LNSADPECLV NWSREVSACS
PPLSF
//
