ID A0A1F8P8N7_9CHLR Unreviewed; 803 AA.
AC A0A1F8P8N7;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 13-SEP-2023, entry version 14.
DE SubName: Full=DNA internalization-related competence protein ComEC/Rec2 {ECO:0000313|EMBL:OGO19462.1};
GN ORFNames=A2144_08165 {ECO:0000313|EMBL:OGO19462.1};
OS Chloroflexi bacterium RBG_16_50_9.
OC Bacteria; Chloroflexota.
OX NCBI_TaxID=1797643 {ECO:0000313|EMBL:OGO19462.1, ECO:0000313|Proteomes:UP000177272};
RN [1] {ECO:0000313|EMBL:OGO19462.1, ECO:0000313|Proteomes:UP000177272}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGO19462.1}.
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DR EMBL; MGNK01000189; OGO19462.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F8P8N7; -.
DR Proteomes; UP000177272; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 47..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 240..263
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..284
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 290..307
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 314..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 337..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 375..397
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 403..435
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 442..461
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 473..492
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 524..541
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 557..755
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 803 AA; 87024 MW; E17A6AF524315A00 CRC64;
MLLIYLSCAW VAGIFLGSRV NLPLALSLAG LVPLPLLLFF RQHRKPVILA GMMVFTLFTG
AAYANTSLNT VSESSLRFYN DQGIVAIKGM VSGDPDVRDK NTHLKYSASE ITWGERWTEV
EGTALVFVPR YPVYGYGDVL LVTGELKTPP QFDDFDYRGY LAHQGIYATI LYPKVELLDT
GHGFKPLTWV YSLRALLAEN LGRVLPEPQA SLAQGIVLGM RGNIPLSLNN DFARSGTTHL
LAISGLNLSV MAGILLSIGL WFFGRRHYLY IWLALGAIWF YVLITGVHPP VVRAALMASL
FLMAEFLGRQ RSAIVALTFS AAIMVGISPY LLGDAAFQLS FLAMAGLIFI APFFRDRGRR
VVTAWWGEKG IGTPVASIAS DTLSATMGAI IAVWPVVAYH FGIISLAAPL ATLLALPALS
GIIVIGTLAA VLGLVALPLA QVLGWVAWLF LSYMITVVGG LGSPPASSIE GTVSIAFVWG
YYLVLALAVW LGHHRKIFTH LMSGAAARVR SAVGAFNLSR AIKWVVPPLA IIAVLISYTA
ATMPDGNLRV SFLDVGEGDA ILIQKGSQQV IIDGGSSPQA ISLALSGKMP FWDRAIELVV
LTHTHQDHLA GLLEVLRRYQ VKQVLYTRWD VESPAYQEWL RLIAELGVPV TTARAGQLLN
LGDGVVVNVL SPQIAFLGTE SDIDNNSLVL RLSTGSISFL FTADIMNEAE WELISNRADL
TSTVLKVAHH GSDTSTTPEF LAVVNPRVAV ISVSADNRFG HPGDDVVSRL EQKLGVGNVY
RTDRQGTIEF TTDGDRLWVS VAK
//
