ID A0A1F8PH70_9CHLR Unreviewed; 1633 AA.
AC A0A1F8PH70;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 28-JUN-2023, entry version 21.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=A2Y54_00425 {ECO:0000313|EMBL:OGO22497.1};
OS Chloroflexi bacterium RBG_16_51_16.
OC Bacteria; Chloroflexota.
OX NCBI_TaxID=1797644 {ECO:0000313|EMBL:OGO22497.1, ECO:0000313|Proteomes:UP000178729};
RN [1] {ECO:0000313|EMBL:OGO22497.1, ECO:0000313|Proteomes:UP000178729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGO22497.1}.
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DR EMBL; MGNL01000127; OGO22497.1; -; Genomic_DNA.
DR Proteomes; UP000178729; Unassembled WGS sequence.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 7.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR45569; SENSOR PROTEIN KDPD; 1.
DR PANTHER; PTHR45569:SF1; SENSOR PROTEIN KDPD; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF13185; GAF_2; 5.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 6.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 7.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT DOMAIN 1370..1594
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT REGION 1612..1633
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1633 AA; 179727 MW; 7CC736733D3E44EB CRC64;
MSILEKENGL LRRITAVGIP DETLKELIAR KQPLTALQHL MQPQFKISHS YFIPADQTPI
LPADVHYVYS TYEVQSEVPK GNAWNPDDFL IFPIEDSKGE ILGLISVDDP SDGLRPDLAT
IDSIEAFSVQ AALVLAQNKL ISGLRDRVAT LDSGLQRQQK LLDVTQNDLP VLLRKDLEAT
ISLHNLDQRA QRVRAGLAIT EQVSRQLDSS SALLALGRET LTQLGMTAAM VAENSADGPR
LLHTLGSVPR TTNVDALFGQ RNPLRTCMQT GEAILVSSMD DSEEWRDSPL LTSLRVKSFI
CLPVYIQEKP VAAMLALSPE TMPSFTAEDR QVYFQIARQS SVILQNISLL NETRRRLQEV
NLLLDFSRRL TGLDSDEILK TLLNSAMHVI PSAHAGTVLV WNQQAGLLLP LAVSGYADNE
TMGRIQYRSG EALPGAAYAE KRIRRVDEVN FARDYVLIPE NITLYRQAVG GRMPVSCIHV
PILTGEQCLG VLTLDNFNTQ GAFKSDDETL LISLTQQVAL SFENVRLMQA MRERAGQLQA
LNDVATSLTS SLRSDQLVGS LLDNLTPILP FDSAAFWFRE GDQLTVVATR GYPDTEDPLG
ASVGVTENAL FDKMSQTGQA ISIGDVREDA RFPRVEAPRL SWLGIPLVSK GVLAGVLALE
KWQAYYYAPE QIQVGLTFAS QAAVALENAR LYEDSLNRAE ELDERSQRLA LLNRFSSSLS
GLLDIDQILQ LAAEELLKAV GAERVSVVTF ENNQAIWKTT VPRMKINLPR LLPEAPIFVH
LRESLGVFNT DDAHNEGDVV PLKDMLGEET TALMVISIPS GQNLAGLLFA QSTGAAHFSP
VEIELARTIV NQVSISLDNA RLYQSNLQTA NRLNLLHETS SEVSSHSEAD EIYLSVHKAA
EKLMRVDSIA IGLLVEQSGE IEGVYLVEGK MRSLPIRVSK ERGLNGEVIR TGQSILLNDR
AKIQAAGGRG FGKSEDGQSM ILVPMMAGGK VRGVLSVQSS EPGAYSNEDQ QILGTLANQA
IVGIQNEQLL TETRRLTQEL DGRVTERTSQ LEHDQHHTET LLKILTEVSS SLDLDRALNR
TLSLLNNTIG AEQGTIMLLH PEDNLLHFQA GYGYVSERSD IASRNLTLKI GEGLAGWVVR
NRQPALVGDL HADPRWLKSS EGIDHRSCIA IPMIVGDDVI GVLLVFHRAV NYFNPDMQNL
VKAVAAQVAV AINNAHLYEL IRDQADRLGV MLRKEQEDAS RSQAILAAVA DGVLVTGANN
QISFINPSIE RILHVEKSKL LGSPLDSFAG LFGKSSGAWM TTIRRWSEEP SIYQAGDTYA
EQLELEDGRI ALVHLAPVIM ENEFLGTVSI FSDITQQVEV DKMKSEFVST VSHELRTPMT
SIKGYVDLLQ MGAAGALNDN QEHFVDIVSN NINRLNMLLD ELLDISRFEA GHVIITPAAV
DLVHLAEEAV IKIKQRSEKE NKPMTIKLAI EEDLPQIIGD AQHVRTILNH LLDNAYNYTP
ENGVISVQII SGEQDDVQVD IKDNGIGIPT ANQEQVFERF WRGDDERVLA TPGTGLGLPI
VRQLVEMHKG KIWLKSLGVP GEGSVFSFTL PKHVARDRKA DMRTARLYGE GEDMFIPPKD
PPRDMGTPGA SSS
//
