ID A0A1F8R6L4_9CHLR Unreviewed; 142 AA.
AC A0A1F8R6L4;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=B12-binding domain-containing protein {ECO:0000259|PROSITE:PS51332};
GN ORFNames=A2Z05_07230 {ECO:0000313|EMBL:OGO43344.1};
OS Chloroflexi bacterium RBG_16_60_22.
OC Bacteria; Chloroflexota.
OX NCBI_TaxID=1797656 {ECO:0000313|EMBL:OGO43344.1, ECO:0000313|Proteomes:UP000179512};
RN [1] {ECO:0000313|EMBL:OGO43344.1, ECO:0000313|Proteomes:UP000179512}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- COFACTOR:
CC Name=adenosylcob(III)alamin; Xref=ChEBI:CHEBI:18408;
CC Evidence={ECO:0000256|ARBA:ARBA00001922};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGO43344.1}.
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DR EMBL; MGNX01000094; OGO43344.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F8R6L4; -.
DR STRING; 1797656.A2Z05_07230; -.
DR Proteomes; UP000179512; Unassembled WGS sequence.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0016853; F:isomerase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR InterPro; IPR006159; Acid_CoA_mut_C.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR NCBIfam; TIGR00640; acid_CoA_mut_C; 1.
DR PANTHER; PTHR48101:SF1; METHYLMALONYL-COA MUTASE, LARGE SUBUNIT; 1.
DR PANTHER; PTHR48101; METHYLMALONYL-COA MUTASE, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF02310; B12-binding; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
PE 4: Predicted;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 7..139
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
SQ SEQUENCE 142 AA; 15250 MW; DAABA461D5267337 CRC64;
MKTNNNRIRV LLAQFSLETH SRGIFTVAGM LKDAGMEVIY IGNSSPEEII EAAVQENVDV
VGVSTLTGGE LVLGAKLMAL AGQKDIKDEK LFIMGGIFPQ RDEPELIKLG FYALFGPGAT
REEITGSIRE AVAARAKVAG KK
//
