ID A0A1F8RJ15_9CHLR Unreviewed; 905 AA.
AC A0A1F8RJ15;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 13-SEP-2023, entry version 22.
DE RecName: Full=HD-GYP domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=A2Z30_01335 {ECO:0000313|EMBL:OGO47674.1};
OS Chloroflexi bacterium RBG_16_64_43.
OC Bacteria; Chloroflexota.
OX NCBI_TaxID=1797659 {ECO:0000313|EMBL:OGO47674.1, ECO:0000313|Proteomes:UP000179556};
RN [1] {ECO:0000313|EMBL:OGO47674.1, ECO:0000313|Proteomes:UP000179556}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGO47674.1}.
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DR EMBL; MGOA01000106; OGO47674.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F8RJ15; -.
DR STRING; 1797659.A2Z30_01335; -.
DR Proteomes; UP000179556; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00077; HDc; 1.
DR CDD; cd12914; PDC1_DGC_like; 1.
DR CDD; cd12915; PDC2_DGC_like; 1.
DR Gene3D; 3.30.450.40; -; 2.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR037522; HD_GYP_dom.
DR InterPro; IPR006675; HDIG_dom.
DR NCBIfam; TIGR00277; HDIG; 1.
DR PANTHER; PTHR45228:SF1; CYCLIC DI-GMP PHOSPHODIESTERASE TM_0186; 1.
DR PANTHER; PTHR45228; CYCLIC DI-GMP PHOSPHODIESTERASE TM_0186-RELATED; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF13185; GAF_2; 2.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF13487; HD_5; 1.
DR SMART; SM00065; GAF; 2.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF55781; GAF domain-like; 2.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS51832; HD_GYP; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 278..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 299..352
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 721..905
FT /note="HD-GYP"
FT /evidence="ECO:0000259|PROSITE:PS51832"
SQ SEQUENCE 905 AA; 97672 MW; 7EC5416E2DDA94ED CRC64;
MRLPLFGLVL LAILPAFAVV LSFGISERRS EAARAKQEAL DFAHLAAHDQ QHVVNSTREL
LILLSGQDEV WPTSGHECSG YVAGVMPAYP SVANLGAATL DGNIYCSAVP LTAPVNITDR
GYFQRALSSG DFSVGEFQVG RITGRVAINM GYPIHDESGA LHGVVYAALS LDWLGQLAAG
AGLPLGSSVT VIDSLGTVLA RFPEEEGWVG QEVPEAPLYM AITQGQGEGV FEAVGLDGEH
RLFGYTSLVA DRPGAVYVSV GIPAAQAYAR LDSAITRAGL ALGGLFLLGL VATWAGSEFF
IMRRTRTLVE VARKLAAGDL SARTGITHAG DELGEVTAAL DTLAETNQNR LEERDRALAQ
LSTVVRALRT LGESNQALVR AENESDLLQN VCQVIVTSGG YIAAWVAFAE QDEARTIRPM
AHAGLIGEDL DSLPLSWGEG PQGENPVGLA IRSGRPQVFQ DLGAAPFHDA WTRTTLDRGC
ASVLVLPLGS APGEVLGVLA IYAGEQGGFA VEEEVLLLEQ MARDLAYGIG ALRTRRARES
IESQLERQLD RLQSLRAIDN AIVSSLDLKV TLAVLLDQAT TQLHAEAADV LLLDPHSLRL
EHFASRGFRT RALEHTKLRL GEGQAGRAAA TRVPVRIDDL RVSPGTLARA PLLAEEGFVG
YYALPLIAKG EVKGVIEIFG RKPFVIDREW EEFLATLAGQ AAVAIDSSRL FDGLQRSNAD
LTLAYDATIE GWSRALDLRD KETEGHTQRV AQMTEQMARE MGFSETALLH IRRGALLHDI
GKMGVPDTVL LKPGALTEAE WEVMRQHPVY AYELLSPIAY LAPAIDIPYA HHEKWDGSGY
PRGLVGEAIP LAARVFAVID VWDALRSDRP YRAAWPAAKA LEHIRAGAGS HFDPKVVEVF
LRMRW
//
