ID A0A1F8S0T5_9CHLR Unreviewed; 181 AA.
AC A0A1F8S0T5;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=Metallo-beta-lactamase domain-containing protein 1 {ECO:0000256|ARBA:ARBA00014856};
DE AltName: Full=Endoribonuclease MBLAC1 {ECO:0000256|ARBA:ARBA00032988};
DE Flags: Fragment;
GN ORFNames=A2V84_08440 {ECO:0000313|EMBL:OGO53492.1};
OS Chloroflexi bacterium RBG_16_70_13.
OC Bacteria; Chloroflexota.
OX NCBI_TaxID=1797662 {ECO:0000313|EMBL:OGO53492.1, ECO:0000313|Proteomes:UP000177511};
RN [1] {ECO:0000313|EMBL:OGO53492.1, ECO:0000313|Proteomes:UP000177511}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleotidyl-ribonucleotide-RNA + H2O = a 3'-end
CC ribonucleotide-RNA + a 5'-end (5'-phospho)-ribonucleoside-RNA + H(+);
CC Xref=Rhea:RHEA:68096, Rhea:RHEA-COMP:15179, Rhea:RHEA-COMP:17355,
CC Rhea:RHEA-COMP:17428, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:74896, ChEBI:CHEBI:138282, ChEBI:CHEBI:173118;
CC Evidence={ECO:0000256|ARBA:ARBA00029337};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:68097;
CC Evidence={ECO:0000256|ARBA:ARBA00029337};
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGO53492.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MGOD01000090; OGO53492.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F8S0T5; -.
DR Proteomes; UP000177511; Unassembled WGS sequence.
DR CDD; cd07711; MBLAC1-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR039344; MBLAC1.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR PANTHER; PTHR23200:SF48; METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR23200; UNCHARACTERIZED; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
FT DOMAIN 16..173
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:OGO53492.1"
SQ SEQUENCE 181 AA; 19739 MW; 266AE2FDE66EC1DF CRC64;
VHLLHAGYAR DDGRVGGSVT LVRDGDAIIV ADPGMVARRG LILEPLAALG VTPEAVTHVF
LSHHHPDHTV NIALFPNAEV VDFWARYRDD LWLDHAGDGH ELAPHSRLWL TPGHTEEDAT
LVVEADDATY ALTHLWWFGD RTPLVDPLAF DQAAIERGRA RVLAAADVVI PGHGAPFRVR
G
//
