ID A0A1F8SC88_9CHLR Unreviewed; 210 AA.
AC A0A1F8SC88;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE SubName: Full=Methyltransferase {ECO:0000313|EMBL:OGO57453.1};
GN ORFNames=A2Z32_02335 {ECO:0000313|EMBL:OGO57453.1};
OS Chloroflexi bacterium RBG_16_69_14.
OC Bacteria; Chloroflexota.
OX NCBI_TaxID=1797661 {ECO:0000313|EMBL:OGO57453.1, ECO:0000313|Proteomes:UP000178994};
RN [1] {ECO:0000313|EMBL:OGO57453.1, ECO:0000313|Proteomes:UP000178994}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGO57453.1}.
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DR EMBL; MGOC01000043; OGO57453.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F8SC88; -.
DR STRING; 1797661.A2Z32_02335; -.
DR Proteomes; UP000178994; Unassembled WGS sequence.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02070; corrinoid_protein_B12-BD; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 1.10.1240.10; Methionine synthase domain; 1.
DR InterPro; IPR003759; Cbl-bd_cap.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR036594; Meth_synthase_dom.
DR PANTHER; PTHR45833; METHIONINE SYNTHASE; 1.
DR PANTHER; PTHR45833:SF1; METHIONINE SYNTHASE; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF02607; B12-binding_2; 1.
DR SMART; SM01018; B12-binding_2; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF47644; Methionine synthase domain; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51337; B12_BINDING_NTER; 1.
PE 4: Predicted;
KW Cobalt {ECO:0000256|ARBA:ARBA00023285};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000313|EMBL:OGO57453.1};
KW Transferase {ECO:0000313|EMBL:OGO57453.1}.
FT DOMAIN 1..87
FT /note="B12-binding N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51337"
FT DOMAIN 87..210
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
SQ SEQUENCE 210 AA; 21982 MW; A09ED8A3020843D8 CRC64;
MADLEVLIAA IQDGDRATAT RVTADAIRDE MDPQSILDAM TAAMAEVGRR FQCNEVYVPE
MLISARAMKE ATALLEPVLI KADIRPEWTA VIGTINGDLH DIGKNLVAMM WRGANIKVVD
LGTNVPAERF VEAARDHQAS LIGISALLTT TMTGMRDAVA AIRAADLPGV RIMVGGAPVT
PEFAAEIGAD AYAPDAASAV DVAKGAVAAG
//
