ID A0A1F8SGL9_9CHLR Unreviewed; 616 AA.
AC A0A1F8SGL9;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=Penicillin-binding protein 2 {ECO:0008006|Google:ProtNLM};
GN ORFNames=A2V85_01290 {ECO:0000313|EMBL:OGO59029.1};
OS Chloroflexi bacterium RBG_16_72_14.
OC Bacteria; Chloroflexota.
OX NCBI_TaxID=1797663 {ECO:0000313|EMBL:OGO59029.1, ECO:0000313|Proteomes:UP000176218};
RN [1] {ECO:0000313|EMBL:OGO59029.1, ECO:0000313|Proteomes:UP000176218}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGO59029.1}.
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DR EMBL; MGOE01000022; OGO59029.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F8SGL9; -.
DR STRING; 1797663.A2V85_01290; -.
DR Proteomes; UP000176218; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 55..212
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 261..562
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
FT REGION 593..616
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 616 AA; 65997 MW; 2ACBCD9BEB972305 CRC64;
MLGRTDSRFR ALLVLVAFVV AAGSLTVRLA YWQVARHDDL AAMARAQTSL RYEVPTDRGS
IYDRSGTVVL ATSVARDLLA ATPKLLTPPR RAEVAETLVG VLGLDAEAAD TLRTRMSTDD
EYVVIATNLE PAVSDRIRAL SSGDDPALAG LILEPEAVRV YPQPGGGPGT TLAAHILGFV
NRAGEGQYGV EQYYQDELAG TPRAVAAQRD AARNPIPDTS IVLDPGTPGQ DLTLTIDAGL
QVAVEQELLA AWIADRAKAV SAIVLDPYTG EVYAWASYPS YDANDYKSIA AEDPSRFIDP
LVSTVYEPGS VFKMFTAVAA LGNGTVTPKT KIKDTGTLRL DRGEARVDDA DHRAMGWMTF
EDAIAYSRNV VAAKVALKLG KTTRAASQVL YDAWRKMGFG APSGVDLANE VGGIVRDPAQ
RPWHQIDLAN GAFGQGIAVT PVQLAQAYAA MVNGGTLVQP RVVRSVGTTE TSTIDRGTVM
TPAMSATLRK LMIHVVTEVD FYRDRTVIPG FEVGGKTGTA QIWDADKGKW KVNKFNYSFV
GYIAREPGRP DLVVAVRIEE GTPTVIRRGL LEMPVMSFEL FRRIAHNAIN TPDLVPVRDP
ATSPAAPAAS PGPGVP
//
