ID A0A1F8TP78_9CHLR Unreviewed; 437 AA.
AC A0A1F8TP78;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 13-SEP-2023, entry version 20.
DE SubName: Full=Thymidine phosphorylase {ECO:0000313|EMBL:OGO73621.1};
GN ORFNames=A3G84_01760 {ECO:0000313|EMBL:OGO73621.1};
OS Chloroflexi bacterium RIFCSPLOWO2_12_FULL_71_12.
OC Bacteria; Chloroflexota.
OX NCBI_TaxID=1797673 {ECO:0000313|EMBL:OGO73621.1, ECO:0000313|Proteomes:UP000179700};
RN [1] {ECO:0000313|EMBL:OGO73621.1, ECO:0000313|Proteomes:UP000179700}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SIMILARITY: Belongs to the thymidine/pyrimidine-nucleoside
CC phosphorylase family. {ECO:0000256|ARBA:ARBA00006915}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGO73621.1}.
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DR EMBL; MGOO01000069; OGO73621.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F8TP78; -.
DR Proteomes; UP000179700; Unassembled WGS sequence.
DR GO; GO:0004645; F:1,4-alpha-oligoglucan phosphorylase activity; IEA:InterPro.
DR GO; GO:0016154; F:pyrimidine-nucleoside phosphorylase activity; IEA:InterPro.
DR GO; GO:0006206; P:pyrimidine nucleobase metabolic process; IEA:InterPro.
DR GO; GO:0006213; P:pyrimidine nucleoside metabolic process; IEA:InterPro.
DR Gene3D; 3.40.1030.10; Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain; 1.
DR Gene3D; 3.90.1170.30; Pyrimidine nucleoside phosphorylase-like, C-terminal domain; 1.
DR InterPro; IPR000312; Glycosyl_Trfase_fam3.
DR InterPro; IPR017459; Glycosyl_Trfase_fam3_N_dom.
DR InterPro; IPR036320; Glycosyl_Trfase_fam3_N_dom_sf.
DR InterPro; IPR035902; Nuc_phospho_transferase.
DR InterPro; IPR036566; PYNP-like_C_sf.
DR InterPro; IPR013102; PYNP_C.
DR InterPro; IPR018090; Pyrmidine_PPas_bac/euk.
DR InterPro; IPR017872; Pyrmidine_PPase_CS.
DR InterPro; IPR000053; Thymidine/pyrmidine_PPase.
DR NCBIfam; TIGR02644; Y_phosphoryl; 1.
DR PANTHER; PTHR10515; THYMIDINE PHOSPHORYLASE; 1.
DR PANTHER; PTHR10515:SF0; THYMIDINE PHOSPHORYLASE; 1.
DR Pfam; PF02885; Glycos_trans_3N; 1.
DR Pfam; PF00591; Glycos_transf_3; 1.
DR Pfam; PF07831; PYNP_C; 1.
DR PIRSF; PIRSF000478; TP_PyNP; 1.
DR SMART; SM00941; PYNP_C; 1.
DR SUPFAM; SSF52418; Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain; 1.
DR SUPFAM; SSF47648; Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain; 1.
DR SUPFAM; SSF54680; Pyrimidine nucleoside phosphorylase C-terminal domain; 1.
DR PROSITE; PS00647; THYMID_PHOSPHORYLASE; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 346..420
FT /note="Pyrimidine nucleoside phosphorylase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00941"
SQ SEQUENCE 437 AA; 46144 MW; 28FB06D860D176B1 CRC64;
MSSRIVELIE RKRDGGKLSQ DELDRLVLGF TKGDVPEHQM AAFCMAVVFR GMDDEETAWL
TDSMVRSGRR LYLSKFGRVV DKHSTGGIGD KVTLVVAPLV AACGAPVAKM SGRGLGITGG
TLDKLESFRG YRVDLTTDEF LAQLERIGIV VTGQTKELAP ADGLIYALRD QTGTVGSIPL
IASSIMSKKI ASGAQAVVLD VKVGEGAFMR TLGEARKLAR LMVAIGKAHG IRVTAELTAM
DAPLGRAVGN ALEAREAIES LRGEGPKDLR EVALAAGAEM LVLARRAPTR AAGRAMLVAA
MRTGAGTAKL RELVAAQGGD AGMVDDVARL PRARTVRTLR AERTAYVGRI AASAIGLASV
RLGAGREKKG EAIDHATGVV LRASVGEAVA RGGPYAEIHS NGRPGDAEAL ELVRGAFTWR
QTAPPRPRLV LDRIASR
//
