ID A0A1F9VQE0_9BACT Unreviewed; 539 AA.
AC A0A1F9VQE0;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:OGS05111.1};
GN ORFNames=A3G41_01870 {ECO:0000313|EMBL:OGS05111.1};
OS Elusimicrobia bacterium RIFCSPLOWO2_12_FULL_59_9.
OC Bacteria; Elusimicrobiota.
OX NCBI_TaxID=1797952 {ECO:0000313|EMBL:OGS05111.1, ECO:0000313|Proteomes:UP000176685};
RN [1] {ECO:0000313|EMBL:OGS05111.1, ECO:0000313|Proteomes:UP000176685}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGS05111.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MGUX01000043; OGS05111.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F9VQE0; -.
DR STRING; 1797952.A3G41_01870; -.
DR Proteomes; UP000176685; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd02068; radical_SAM_B12_BD; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR034466; Methyltransferase_Class_B.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR PANTHER; PTHR43409:SF17; MG-PROTOPORPHYRIN IX MONOMETHYL ESTER OXIDATIVE CYCLASE 66KD SUBUNIT; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01123; methyltransferase_(Class_B); 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00022485};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00022485};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022485}.
FT DOMAIN 46..179
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
FT DOMAIN 239..461
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 539 AA; 59973 MW; 58ECD3BBA832709D CRC64;
MFAALLNGNK KKLPTLQEYI DRGFAPAGGV TDILLIFPPT SIADRYGKAD VGDAGGDLPP
LGVTTIAAYL REKGFGVGLL DGCALGLGHN QIIDIIRAKD PKAIGISSTT YALPSGLALA
RRIRSEFPDK LVILGGAHAN AVPLESAQDY PEFDLVVYGE GELSAEQILG EYKKLGYDRT
SFLEGEAFLS GVKGIVYRNA GGACVLNPEM PNIKNLDTLP LPARDLLPME IYLPLPNQYK
KPPVVHMVVI RGCPYACSFC DQAGTGGRTR SPAKAVEEIV HVVEKYGARE ISFWDDTMSF
NRVWMRKFCQ LLIEADTGVI WSCYAAVNTV DRQLLDLMHK AGCWNIFYGI ETGVPELMKN
IESHRKNTSP EKIRKVMQET KDAGIEIRGS FMIALPGETP ELAAETIKFA IELDPDYAQF
SITTPYPGTH LYDDIRQGKW GKLTTADFSE FQGWNVVFLP NGYKSQKEVW EMERKAFRSF
YFRPKYILKK FLQTRSLEDI KRYFKGLRLL IGGFAYGPMP PHIREVEGRT PGPEARVLH
//
