ID A0A1G0JAC1_9GAMM Unreviewed; 1084 AA.
AC A0A1G0JAC1;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Diguanylate cyclase {ECO:0008006|Google:ProtNLM};
GN ORFNames=A3H44_00815 {ECO:0000313|EMBL:OGT71370.1};
OS Gammaproteobacteria bacterium RIFCSPLOWO2_02_FULL_57_10.
OC Bacteria; Pseudomonadota; Gammaproteobacteria.
OX NCBI_TaxID=1798299 {ECO:0000313|EMBL:OGT71370.1, ECO:0000313|Proteomes:UP000178443};
RN [1] {ECO:0000313|EMBL:OGT71370.1, ECO:0000313|Proteomes:UP000178443}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGT71370.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MGYS01000060; OGT71370.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G0JAC1; -.
DR STRING; 1798299.A3H44_00815; -.
DR Proteomes; UP000178443; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 3.
DR PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF13185; GAF_2; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00086; PAC; 3.
DR SMART; SM00091; PAS; 3.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 2.
DR PROSITE; PS50112; PAS; 3.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 84..104
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 110..180
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 412..482
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 486..538
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 535..581
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 606..660
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 692..824
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 833..1084
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 1084 AA; 121661 MW; 66D889CAB0F24BF7 CRC64;
MIDFMAGLEG EISPYIDIEI HDGEPRGEVS LLYHSDNVSH DTRAAEQQLQ MQLPLTIGGR
EWTLLFSDTP EFRSIVMPER RSPLVLLTGG LISALLSMVA LLLIKGRVSA ESRFRRLFNH
AGDGIVVLDR NYRVIDCNIM APRLLGYRRD ELLSMQPLDV VSPSEYERLS RELPVMTTGN
AHLAQWTLLK KDGTTLPTEI HASRLDDQHY IAIIRDYSAH RKAERRIHYL THLYQAMTET
NQAIIRMSDE QELFPLVCRI AVELGGMRMA WIGQLNPDTD HIEPKASFGS GLGYLDGLVI
STRNDTPQGR GPTSRALREN SPIIINHYMA DPSTRPWHDL AREFGWGASG AFPVQRSGNP
FAVLNVYHSD VGAFDDEIIA LLSELVSDIS FALDNFDREI KRQQAAHALA ESEARITTIM
ENVSACIYLK DIEGRYLYAN QPVLDLWGVE LDDVIGADDS KFLDPETAQN IRTNDSLVLE
HGQTVHKEET NIVASTGAVV TYWSTKLPLR RVDGTIYALC GISTDISERK KLETTLRLQA
QVFESNRDGI VITNADNRII SVNRAYTQIT GYSEIEALGE NPSIIASGHH DKTFYEAMWQ
QIDKHGHWQG ELLNRRKNGN TYPQWLSINV VRNAEGRVVQ YIGMLTDLSE YKASEERIQF
LSNYDPLTRL PNRQLLQDLA LHAIASARKT HSPVALMFID LDRFKLVNET LGHQVGDNLL
KQLADRLQQH LDPDFTLCRQ GGDDFILLLP DTDAEAAAHT AGSILDIVTR PFLMGDQKLT
LTASIGIAQF PEDAADFGEL VQSADAALFR AKQSGRNNFQ FFTREMHEQA SALLHMENEL
RQALEREELV LHYQPQFDAN TGKLTGAEAL VRWMHPVRGL VSPAHFIPVA EESGLIIEIG
NWVMRKAVCQ IALWQNQGLN VVPVAVNLSV VQFRQKSFYQ DVVDALKACN LAPSLLELEI
TEGIAMDDSE RTLDLLQDLH ELGISLAIDD FGIGYSSLNY LKRFRIDKLK IDQSFVRGLG
HDSEDEAIVT AIIGMAKGLG YRTLAEGVET RQQLDYLHNA GCDEIQGYLL GRPIPADEFV
KLMQ
//
