ID A0A1G0QN62_9BACT Unreviewed; 492 AA.
AC A0A1G0QN62;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:OGU49313.1};
GN ORFNames=A2080_12660 {ECO:0000313|EMBL:OGU49313.1};
OS Ignavibacteria bacterium GWC2_36_12.
OC Bacteria; Ignavibacteriota; Ignavibacteria.
OX NCBI_TaxID=1798427 {ECO:0000313|EMBL:OGU49313.1, ECO:0000313|Proteomes:UP000178676};
RN [1] {ECO:0000313|EMBL:OGU49313.1, ECO:0000313|Proteomes:UP000178676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGU49313.1}.
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DR EMBL; MGZZ01000151; OGU49313.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G0QN62; -.
DR STRING; 1798427.A2080_12660; -.
DR Proteomes; UP000178676; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR034466; Methyltransferase_Class_B.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR PANTHER; PTHR43409:SF7; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE; 1.
DR PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01082; B12-binding_domain_containing; 1.
DR SFLD; SFLDG01123; methyltransferase_(Class_B); 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00022485};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00022485};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022485}.
FT DOMAIN 1..150
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
FT DOMAIN 201..423
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 492 AA; 57674 MW; 6FC36BB73A4ADDF7 CRC64;
MKILIGQSYF RILDPKELER KMPYPPLGTL YAATILRDLN HEIIFFDSMM SKNPDEFLLQ
IEKEKPDLLL LYDDEFNYLT KMCLSRMREK AIEFIKKGKT HHIPVVVYSS DATDFPQSYL
CEGCDAIIYG EGEETLKEVV ASLRNNSFDL DKFQIDGLKF LQNGSVHVTP KRKLLENLNS
LADPDYSFID MNEYRNEWLN NHGFFSTNIS TTRGCPYRCN WCAKPIYGQT YDSITPNRVV
NQIKNFVEKY SVQHLWITDD IFGLKPGWIK EFSAELKKSN IKIKYKCLTR PDLLLRGNTI
NDLKESGCKD IWIGAESGSQ KILDAMDKGT TVKQIYEASK KVKEAGMDIS FFIQFGYTGE
TREDINLTRK MIRDCLPSDI GISVSYPLPG TLFYERVKNK LREKTNWEDS DDLDPMLRGV
YERNFYKILH RFVHTEYRIF KILRNKRWKK VHYFLFYLVK MIFLKIKMSR FLKEEKLSSS
NSILVDLKNI DT
//
