ID A0A1G0RNV9_9BACT Unreviewed; 450 AA.
AC A0A1G0RNV9;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 12.
DE SubName: Full=Na+ dependent nucleoside transporter domain-containing protein {ECO:0000313|EMBL:OGU61796.1};
GN ORFNames=A2V66_12935 {ECO:0000313|EMBL:OGU61796.1};
OS Ignavibacteria bacterium RBG_13_36_8.
OC Bacteria; Ignavibacteriota; Ignavibacteria.
OX NCBI_TaxID=1798432 {ECO:0000313|EMBL:OGU61796.1, ECO:0000313|Proteomes:UP000177879};
RN [1] {ECO:0000313|EMBL:OGU61796.1, ECO:0000313|Proteomes:UP000177879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the concentrative nucleoside transporter (CNT)
CC (TC 2.A.41) family. {ECO:0000256|ARBA:ARBA00009033}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGU61796.1}.
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DR EMBL; MHAE01000023; OGU61796.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G0RNV9; -.
DR Proteomes; UP000177879; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005337; F:nucleoside transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR008276; C_nuclsd_transpt.
DR InterPro; IPR011657; CNT_C_dom.
DR InterPro; IPR002668; CNT_N_dom.
DR InterPro; IPR011642; Gate_dom.
DR PANTHER; PTHR10590; SODIUM/NUCLEOSIDE COTRANSPORTER; 1.
DR PANTHER; PTHR10590:SF4; SOLUTE CARRIER FAMILY 28 MEMBER 3; 1.
DR Pfam; PF07670; Gate; 1.
DR Pfam; PF07662; Nucleos_tra2_C; 1.
DR Pfam; PF01773; Nucleos_tra2_N; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..23
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 30..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 108..129
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 224..249
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 286..308
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 329..350
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 394..417
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 429..449
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 11..94
FT /note="Concentrative nucleoside transporter N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01773"
FT DOMAIN 109..209
FT /note="Nucleoside transporter/FeoB GTPase Gate"
FT /evidence="ECO:0000259|Pfam:PF07670"
FT DOMAIN 229..447
FT /note="Concentrative nucleoside transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07662"
SQ SEQUENCE 450 AA; 48014 MW; 0CF83185BDC853F7 CRC64;
MDIVSLLRGI LGIIILVGIA FLISNNKKKV NWKLVGSGLL IQVIFAILII KGEDLGNLFS
PLAWPKEIFK FISSFFVLVL NFTQQGAEFI FGQLALGPGN TKSLGTFFAF QVLPTIIFFA
SLMSLLYYLG IMQRIVQGMA WLMSKLMGTS GAESLSCSAN IFVGQTEAPL MIKPFLKGMT
NSELLTVMTG GMATIAGGVM AAYIQMLGQA FAQTMQIPIR EAQLIFATHL LGASVMAAPA
ALVVSKIMFP ETGEPETKGK VKIDIEKNAS NVIESAAVGA ADGLKLALNV GAMLIAFIAL
IALANYLLQG LGQLLTVNNY LKDTFGQPLS MQLIFGLVLQ FLAYGIGVPW ESSMQFGSLI
GTKVVLNEFV AYLDMSTFIQ SGQLLNEKAI LMSTYALCGF ANFSSIAIQI GGITPLAPNR
QSDLAKLGLK AVIGGTLATL MTATLAGILF
//
