ID A0A1G0T149_9BACT Unreviewed; 531 AA.
AC A0A1G0T149;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=A2W11_05370 {ECO:0000313|EMBL:OGU78353.1};
OS Ignavibacteria bacterium RBG_16_35_7.
OC Bacteria; Ignavibacteriota; Ignavibacteria.
OX NCBI_TaxID=1798434 {ECO:0000313|EMBL:OGU78353.1, ECO:0000313|Proteomes:UP000178403};
RN [1] {ECO:0000313|EMBL:OGU78353.1, ECO:0000313|Proteomes:UP000178403}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGU78353.1}.
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DR EMBL; MHAG01000258; OGU78353.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G0T149; -.
DR Proteomes; UP000178403; Unassembled WGS sequence.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06568; GH20_SpHex_like; 1.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 46..181
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 184..495
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT ACT_SITE 347
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 531 AA; 59735 MW; 1CC4B08A2E392A98 CRC64;
MSTRDIKKRW EIQLTILLFV ITFISCKTPS PTELENISDL TGTINNIIPM PVSVIPAGDW
FIFNKNADIY INPMNSEMEF IGQYLVDKIK PSTGYNIFVL PATGIPANGN IYLTTIGGDP
LLGEEGYELN ITKELIRLIA YKPAGLFRGV QTLRQLFSPL IESKTVQQGE WRIATAAIRD
YPRFQWRGVM LDVARHFFSV EDVKSYIDMA AYYKINRFHI HLADDQGWRI QINSWPNLAV
CGGSTQVGGG SGGYYTQSEY SEIVDYAQQR YITIVPEIDM PGHTNAALAS YAELNKDGIA
PPLYTGIDVG FSELAVDKEI TYSFIDDVIR EISAITPGSY FHIGGDEAPL IDSIDYVHFV
DTVQTIVQSY GKQMIGWDEI SKANLSATSV AQHWANIIVL NAVSQGAKVI MSPASKTYLD
MKYNSSTILG LNWAGYVEVM DAYNWDPATQ MNGITENNIL GLEAPLWTET ILTLDDIEFM
VFPRLAGHSE IGWSPITGRN WNEYKERLAE HGLRWIEMDL NFYRSPQVSW K
//
