ID A0A1G0YEK5_9BACT Unreviewed; 1021 AA.
AC A0A1G0YEK5;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=VWFA domain-containing protein {ECO:0000259|PROSITE:PS50234};
GN ORFNames=A2X48_08460 {ECO:0000313|EMBL:OGV44318.1};
OS Lentisphaerae bacterium GWF2_49_21.
OC Bacteria; Lentisphaerota.
OX NCBI_TaxID=1798573 {ECO:0000313|EMBL:OGV44318.1, ECO:0000313|Proteomes:UP000178513};
RN [1] {ECO:0000313|EMBL:OGV44318.1, ECO:0000313|Proteomes:UP000178513}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGV44318.1}.
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DR EMBL; MHBH01000001; OGV44318.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G0YEK5; -.
DR STRING; 1798573.A2X48_08460; -.
DR Proteomes; UP000178513; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006816; P:calcium ion transport; IEA:UniProtKB-KW.
DR Gene3D; 1.10.10.1320; Anti-sigma factor, zinc-finger domain; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR041916; Anti_sigma_zinc_sf.
DR InterPro; IPR022156; Uncharacterised_YfbK_N.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR InterPro; IPR021908; YfbK_C.
DR InterPro; IPR027383; Znf_put.
DR PANTHER; PTHR10579; CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR; 1.
DR PANTHER; PTHR10579:SF43; LOW QUALITY PROTEIN: EPITHELIAL CHLORIDE CHANNEL PROTEIN-LIKE ISOFORM X1-RELATED; 1.
DR Pfam; PF00092; VWA; 1.
DR Pfam; PF12450; vWF_A; 1.
DR Pfam; PF12034; YfbK_C; 1.
DR Pfam; PF13490; zf-HC2; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 95..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 671..851
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT COILED 393..452
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1021 AA; 112197 MW; DB58D09D0F0A1D3A CRC64;
MTCEKISKMM TDLLAGELSA EEKAILDAHL ASCENCRKEF ADLEKVWKLT EESLRCEPFQ
KQMNPENYEN IYRQAYTRTE KPASKKFFSF KVDHLVMKIA AMLAITAVLA ALLLPAFSTA
REKARRITCG VTSTLGSSEE VSVQISASEV TTKSEDLLKD LDQNGIAPNG PGAKTLPETL
PTSSTRISAG KYAVSKSGAA GYDRRDMDKT VQTAVPANTP SAPPPPLVQP AKPLAKALKE
EMLEKDTRSR GVAGSKTVRA EYKKSDGYVQ GKTAEHAKMK QMLEGVEDVP AIPAPAAAPA
YGYVNAKSEE SKPVTAENSD FLTLPGSVSI AERKSAMASR TPKAGESLKN NEPVLADKAM
DVLEQEIAPS ERQLNESVRL RTFASTTAGQ NILEDKAQKL DSLERKKSLL KIRESGAAAK
EAADEDIDRN GLVDAKQEAM QEEQEGEVAL EKLEVMKTAP SSSALKLPMK KALSDGKESL
QLAQQEAVPH DVMESRIYPI NKEVLRDVGG SDAELVKYLK SKKISFDEGA KIISHSDIGR
IVITNTPEEL QKVEKIFTEL EDAYQRSKEF KNGIPFSDTK QKQFSTFSID VDTASYTMAR
KLLVNGIKPD PTAVRPEEFI NYFDYHYRSP SNSTFAVYLE TAPSVFRPEN YTLRIGVKAR
DIGPDGSRPS VFTIIIDASG SMSQANRMDL VKKSLPQLFD QMKPADKIAI FLCTHRVMNL
VDYVPASNKK TISKLVEGIM PAGVADIEKG LIAAYDSALK HYESGAYNRV ILITDGISNI
GSKSAETILA KVSAARNMGV TNTVVALGGD GDDKFLEAIA NKGDGNYVFI DNEEAANEVF
VKEFEGRFRE IARDVKIQVE FNPVIVNQHR QIGYQNRQLS KADFRNDKVD AGEVGAGQSV
TALYELKLNR KLPKADASIE NPMSQSVCIV RLRYRRADTM DVEEKEFMLP LYEAKTNFAN
ASCGFRLASS VAEFAEFLRF PDVSGIANPG NIMKQVQGVI SEDYKNDGKV SELNTLIKNV
K
//
