ID A0A1G1BCX7_9BACT Unreviewed; 457 AA.
AC A0A1G1BCX7;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Acetylgalactosaminidase {ECO:0000313|EMBL:OGV80577.1};
GN ORFNames=A2X65_05195 {ECO:0000313|EMBL:OGV80577.1};
OS Stygiobacter sp. GWF2_38_21.
OC Bacteria; Ignavibacteriota; Ignavibacteria; Ignavibacteriales;
OC Melioribacteraceae; Stygiobacter.
OX NCBI_TaxID=1801612 {ECO:0000313|EMBL:OGV80577.1, ECO:0000313|Proteomes:UP000176810};
RN [1] {ECO:0000313|EMBL:OGV80577.1, ECO:0000313|Proteomes:UP000176810}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- COFACTOR:
CC Name=NAD(+); Xref=ChEBI:CHEBI:57540;
CC Evidence={ECO:0000256|ARBA:ARBA00001911};
CC -!- SIMILARITY: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109
CC subfamily. {ECO:0000256|ARBA:ARBA00009329}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGV80577.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MHBR01000017; OGV80577.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G1BCX7; -.
DR Proteomes; UP000176810; Unassembled WGS sequence.
DR GO; GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR000683; Gfo/Idh/MocA-like_OxRdtase_N.
DR InterPro; IPR049303; Glyco_hydro_109_C.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR006311; TAT_signal.
DR InterPro; IPR019546; TAT_signal_bac_arc.
DR NCBIfam; TIGR01409; TAT_signal_seq; 1.
DR PANTHER; PTHR43818; BCDNA.GH03377; 1.
DR PANTHER; PTHR43818:SF1; GLYCOSYL HYDROLASE FAMILY 109 PROTEIN; 1.
DR Pfam; PF01408; GFO_IDH_MocA; 1.
DR Pfam; PF21252; Glyco_hydro_109_C; 1.
DR Pfam; PF10518; TAT_signal; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51318; TAT; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW NAD {ECO:0000256|ARBA:ARBA00023027}.
FT DOMAIN 55..181
FT /note="Gfo/Idh/MocA-like oxidoreductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01408"
FT DOMAIN 192..358
FT /note="Glycosyl hydrolase 109 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21252"
SQ SEQUENCE 457 AA; 51368 MW; 2DFFDFF100968B10 CRC64;
MSTSRRDFLK TSLMTGAAIG LSNIPTLGND LASLQAPSTK NKNVVGLACE PIPKVRIGFI
GLGMRGPDAV DRMMKIEGVE IKALGDLMPE RVKAVNELVK KAGRPEAIEF SGSEDAWKKM
CERDDIDLIY SCTPWLLHTP IAVYAMKHGK HAAIEVPIAV SLKECWELVD TAEQTRRHCM
MLENCCYDFF EMATLNMARN GVLGEIIHAE CAYLHDLRWL KFDKEKGYQG MWRLNYSEKH
TGNPYPTHGL GPVAQVMDIN RGDRMEYLTS MSTNQFGMSQ YAANKFGKDS ADAKQTYKLG
DMNTTLVRTA KGHTIMIQHD TTSPRPYSRI HLLSGTKGIA QKWPAQKIAL EPKPHEWLKE
DEYKKLMTLY EHPLAKKIGE KAREVGGHGG MDFIMDYRLI HCLRNGLPLD QDVYDGATWS
SIVELSELSV KNKSKSIEVP DFTRGAWKTT KPIEIIS
//
