ID A0A1G1BD91_9BACT Unreviewed; 562 AA.
AC A0A1G1BD91;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=NADH dehydrogenase {ECO:0000313|EMBL:OGV80711.1};
GN ORFNames=A2X65_05945 {ECO:0000313|EMBL:OGV80711.1};
OS Stygiobacter sp. GWF2_38_21.
OC Bacteria; Ignavibacteriota; Ignavibacteria; Ignavibacteriales;
OC Melioribacteraceae; Stygiobacter.
OX NCBI_TaxID=1801612 {ECO:0000313|EMBL:OGV80711.1, ECO:0000313|Proteomes:UP000176810};
RN [1] {ECO:0000313|EMBL:OGV80711.1, ECO:0000313|Proteomes:UP000176810}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- COFACTOR:
CC Name=[2Fe-2S] cluster; Xref=ChEBI:CHEBI:190135;
CC Evidence={ECO:0000256|ARBA:ARBA00034078};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGV80711.1}.
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DR EMBL; MHBR01000017; OGV80711.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G1BD91; -.
DR Proteomes; UP000176810; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
DR CDD; cd00207; fer2; 1.
DR Gene3D; 3.10.20.740; -; 1.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 3.40.50.740; -; 2.
DR Gene3D; 2.20.25.90; ADC-like domains; 1.
DR InterPro; IPR036010; 2Fe-2S_ferredoxin-like_sf.
DR InterPro; IPR001041; 2Fe-2S_ferredoxin-type.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR InterPro; IPR000283; NADH_UbQ_OxRdtase_75kDa_su_CS.
DR InterPro; IPR019574; NADH_UbQ_OxRdtase_Gsu_4Fe4S-bd.
DR PANTHER; PTHR43105:SF15; FORMATE DEHYDROGENASE H; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF13510; Fer2_4; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 2.
DR Pfam; PF10588; NADH-G_4Fe-4S_3; 1.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SMART; SM00929; NADH-G_4Fe-4S_3; 1.
DR SUPFAM; SSF54292; 2Fe-2S ferredoxin-like; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51085; 2FE2S_FER_2; 1.
DR PROSITE; PS51839; 4FE4S_HC3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
DR PROSITE; PS00641; COMPLEX1_75K_1; 1.
DR PROSITE; PS00643; COMPLEX1_75K_3; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022485}.
FT DOMAIN 2..78
FT /note="2Fe-2S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51085"
FT DOMAIN 78..117
FT /note="4Fe-4S His(Cys)3-ligated-type"
FT /evidence="ECO:0000259|PROSITE:PS51839"
FT DOMAIN 216..272
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
SQ SEQUENCE 562 AA; 62885 MW; 76B3E8A000E78393 CRC64;
MPTITIDGKQ IEFKQGQTVI EVAREAGVEI PHFCYHPKLS VSGNCRVCLV EIEKMPKLAI
SCATLAGDGM VVHTNSTKTL EARNAVMEFI LINHPLDCPI CDEAGECKLQ DYAYAHSRGE
SRFEEIKNRK EKRVQLGPRI KFDGDRCISC SRCIRFSDEI AKSNQLTFVN RGDKVTISTF
PGESFDNPYS MNTVDICPVG ALTNNDFRFK SRVWEMSFTN SICVGCARGC NTEIGVRNNE
ILRLTPRQNE EVNSFWMCDN GRLSTFKNVN ADDRIDGTFV RKEGQLQKVS WDEALEVAAK
SLKEYKSNEI AFVGSAFATC EDNFVLLKLA KQLNVTSVDF ARHSVADDQD DILIREDKTP
NTTGAELVIA KSNGAKLEGI YRLIKEGKVK TLFVMEDDLG ALSEEWEQAL GMLDLLIVTA
TNSSKTTALA DIVFPAASYA EKHGTFVNFQ GRVQRIRPAV SLDEMDRALD GMNMSRWDKF
GTKFDKWNQG RKHDAKPSWK ILAQLSSHLG GKIKYEMAEE VFDEISNSVD AFKGLDYDMI
GELGVQLKIL NSESRLATTK SL
//
