ID   A0A1G1BUT3_9BACT        Unreviewed;       695 AA.
AC   A0A1G1BUT3;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE            EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN   ORFNames=A3K19_29695 {ECO:0000313|EMBL:OGV86502.1};
OS   Lentisphaerae bacterium RIFOXYB12_FULL_65_16.
OC   Bacteria; Lentisphaerota.
OX   NCBI_TaxID=1798581 {ECO:0000313|EMBL:OGV86502.1, ECO:0000313|Proteomes:UP000179250};
RN   [1] {ECO:0000313|EMBL:OGV86502.1, ECO:0000313|Proteomes:UP000179250}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=27774985; DOI=10.1038/ncomms13219;
RA   Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA   Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA   Williams K.H., Hubbard S.S., Banfield J.F.;
RT   "Thousands of microbial genomes shed light on interconnected biogeochemical
RT   processes in an aquifer system.";
RL   Nat. Commun. 7:13219-13219(2016).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00034618};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OGV86502.1}.
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DR   EMBL; MHBP01000301; OGV86502.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G1BUT3; -.
DR   Proteomes; UP000179250; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR035093; RelE/ParE_toxin_dom_sf.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   PANTHER; PTHR11070:SF68; DNA HELICASE; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13361; UvrD_C; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF143011; RelE-like; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}.
FT   DOMAIN          236..535
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   BINDING         257..264
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   695 AA;  77575 MW;  ACFE1487614793DB CRC64;
     MELLIADTFT DSLARLTGDE QKAVKTTAFD LQLNPAHPGM QFHKLDKAKD KNFASVRVGR
     DIRLIVHRSD TSLLLCYVGH HDKAYDWARR RRLETHPKTG AAQLVEIRET VTEVVVPVYV
     QMELPAAPKP AVQKRPLFAN MADDELLAYG VPADWLDDAR KATEDTLLAL ADHLPAEAAE
     ALLELATGGK PRAPQAAVVV ANPFDHPDAQ RRFRVMTNVE ELQRALDFPW EKWTVFLHPE
     QRQWVERDYT GPARVAGSAG TGKTIVALHR AAHLARTHAD ARVLLTTFSD TLANALQTKL
     RRLLGNEPRL AERIDVHSLN AIGLRLYKTH AGAATLVSRE IVREVVQDAA RAVGNHKFSL
     HFLLTEWEQV VDAWQLGDWE AYRDVVRLGR KTRLPETQRT VLWTIFERVR AGLRARKLIT
     HAELFISLAA AISKRKKVVF DFAVVDEAQD ISVAHIRFFA ALGGGRPNAL FFAGDLGQRI
     FQQPFSWKAL GVDIRGRSRT LRVNYRTSHQ IRTQADRLLG PVVTDVDGNV EDRSDTVSVF
     NGPPPTILAL KSEDAEVETV GNWMAERAKA GVLAHEFGVF VRSAAQLDRA RAAVQEAGLA
     FKVLDEHVET ASGHVSISTM HLAKGLEFRA VVVMACDDEI LPLQERIETV GDDADLQEVY
     DTERHLLYVA CTRARDHLLV TSVEPASEFL DDTRV
//