ID A0A1G1BW81_9BACT Unreviewed; 1054 AA.
AC A0A1G1BW81;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding domain-containing protein {ECO:0000259|SMART:SM00928};
GN ORFNames=A3K19_33200 {ECO:0000313|EMBL:OGV86993.1};
OS Lentisphaerae bacterium RIFOXYB12_FULL_65_16.
OC Bacteria; Lentisphaerota.
OX NCBI_TaxID=1798581 {ECO:0000313|EMBL:OGV86993.1, ECO:0000313|Proteomes:UP000179250};
RN [1] {ECO:0000313|EMBL:OGV86993.1, ECO:0000313|Proteomes:UP000179250}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- SIMILARITY: Belongs to the complex I 51 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00007523}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGV86993.1}.
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DR EMBL; MHBP01000287; OGV86993.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G1BW81; -.
DR Proteomes; UP000179250; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR CDD; cd02980; TRX_Fd_family; 1.
DR Gene3D; 3.10.20.600; -; 1.
DR Gene3D; 6.10.250.1450; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.50.11540; NADH-ubiquinone oxidoreductase 51kDa subunit; 1.
DR Gene3D; 1.20.1440.230; NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain; 1.
DR InterPro; IPR028261; DPD_II.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR001949; NADH-UbQ_OxRdtase_51kDa_CS.
DR InterPro; IPR011538; Nuo51_FMN-bd.
DR InterPro; IPR037225; Nuo51_FMN-bd_sf.
DR InterPro; IPR019575; Nuop51_4Fe4S-bd.
DR InterPro; IPR037207; Nuop51_4Fe4S-bd_sf.
DR InterPro; IPR019554; Soluble_ligand-bd.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR43578; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR PANTHER; PTHR43578:SF3; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR Pfam; PF01257; 2Fe-2S_thioredx; 1.
DR Pfam; PF01512; Complex1_51K; 1.
DR Pfam; PF14691; Fer4_20; 1.
DR Pfam; PF10589; NADH_4Fe-4S; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR Pfam; PF10531; SLBB; 1.
DR PRINTS; PR00419; ADXRDTASE.
DR SMART; SM00928; NADH_4Fe-4S; 1.
DR SUPFAM; SSF46548; alpha-helical ferredoxin; 2.
DR SUPFAM; SSF142019; Nqo1 FMN-binding domain-like; 1.
DR SUPFAM; SSF142984; Nqo1 middle domain-like; 1.
DR SUPFAM; SSF140490; Nqo1C-terminal domain-like; 1.
DR SUPFAM; SSF51971; Nucleotide-binding domain; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS00645; COMPLEX1_51K_2; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW FMN {ECO:0000256|ARBA:ARBA00022643}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Translocase {ECO:0000256|ARBA:ARBA00022967}.
FT DOMAIN 460..505
FT /note="NADH-ubiquinone oxidoreductase 51kDa subunit iron-
FT sulphur binding"
FT /evidence="ECO:0000259|SMART:SM00928"
SQ SEQUENCE 1054 AA; 112884 MW; 82F3065002C52B40 CRC64;
MAKFSSVKDL EAHRAELAAS YDPNKLRITV CGGTGCNAQG SIKLVDALRA AVTKHGLDQT
VEVKVTGCHG FCEKGPVVVV RPENIFYVCV KAEDADELVE STLKKGKPVE RLLYVDPASG
KTILHEQEVP FYAKQTRVIL AENGHLDPTS IDDYIVRGGY AALSKVLGGW TPEQVIETVK
KSGLRGRGGA GFPTGTKWEI CRKQPGAEKY IICNADEGDP GAYMNRSEIE GNPHMVIEGM
VLGAYAIGAS TAYIYCRAEY PLAIQQLVKG IAKAKQYGLL GRNILGTGMN LEMIIKQGAG
AFVCGEETAL INSIEGKRGM PRPRPPFPAQ AGVFGKPSNI NNVETWANIP IIVNRGPEWY
SGIGSEKSKG TKVFSLVGCV NNTGLVEVPF GTTLRQIVEV IGGGTPGGRK FKAVQMGGPS
GGCIPASQLD TKLDYESLKS LGAIVGSGGM VVMDDRTCMV DLAKYFMEFI QNESCGKCIP
CREGTRRMKE ILEAITRSRR REEDLDALLR MQGIMYLKKL AETIRITSLC GLGQTAPNPV
LSTMRWFRDE YEAHIFDRRC PAGACRELVG SSCQNGCPVG TEVWRYVAHV ARGEYKAAYK
VIRQANPFPS ACARVCHHPC ENSCRAGLTG GEPIAVRSLK RFVVDHVDPK VGAPFVPVAA
ADATRIAVIG AGPSGLSAGH YLSLLGHRVT IFEREAQPGG MLVGAIPAYR LPREVLSKEI
ESLLNGNIEL KCNMTLGKDV TVDGLLKDGY KAVYLALGSH QSKNLGLPGE DVAGVVAGVQ
FLKAHNLQNT ALAKGRVGIV GGGNSAMDAA RVAFRQPGVQ SVTLFYRRTK AEMPAYAEEI
EAGVAEGIKI EELVAPVSVS AKDGKLTGVR FIRNKLGDRD KSGRQSPVPV PGSEFSAELD
TLVVAISEGP ETAGLDGLSL TRWGTLSVNA ESLLTSRPGV FGGGDVVSGP STVIGAVAAG
KNAALMIDRC VRGKLLRTLP KVKLPTVYIE PVEGPEIDET APPVPRAKSP HLPVAQRAKS
FAEVELAYDE ATARCEARRC LRCDLEFTEP VKPA
//
