ID A0A1G1G0D6_9BACT Unreviewed; 388 AA.
AC A0A1G1G0D6;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=RNA methyltransferase {ECO:0000313|EMBL:OGW37484.1};
GN ORFNames=A2010_06955 {ECO:0000313|EMBL:OGW37484.1};
OS Nitrospirae bacterium GWD2_57_9.
OC Bacteria; Nitrospirota.
OX NCBI_TaxID=1801701 {ECO:0000313|EMBL:OGW37484.1, ECO:0000313|Proteomes:UP000176220};
RN [1] {ECO:0000313|EMBL:OGW37484.1, ECO:0000313|Proteomes:UP000176220}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGW37484.1}.
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DR EMBL; MHED01000170; OGW37484.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G1G0D6; -.
DR Proteomes; UP000176220; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0034470; P:ncRNA processing; IEA:UniProt.
DR GO; GO:0009451; P:RNA modification; IEA:UniProt.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd11715; THUMP_AdoMetMT; 1.
DR Gene3D; 3.30.2130.30; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR004114; THUMP_dom.
DR PANTHER; PTHR47313; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K/L; 1.
DR PANTHER; PTHR47313:SF1; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K_L; 1.
DR Pfam; PF01170; UPF0020; 1.
DR SMART; SM00981; THUMP; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
DR PROSITE; PS51165; THUMP; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:OGW37484.1};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00529};
KW Transferase {ECO:0000313|EMBL:OGW37484.1}.
FT DOMAIN 45..156
FT /note="THUMP"
FT /evidence="ECO:0000259|PROSITE:PS51165"
SQ SEQUENCE 388 AA; 43141 MW; 856D11C6570FB6F7 CRC64;
MNKSRILITC PKGLPPILKQ ELLSLGFPVL SEHLSGVHTE GTLEDAQKLN LFVRTGHRVL
YEVKEFSARN AEDLYRVLAG IGWEALIPAE GHICVTSSVE NETIRDSRFA SLKSKDAIVD
RIKERTGQRP DSGPERDRSV VHVYWKEESA VVYLDTSGEP LSRRGYRRIP LAAPMQETLA
AGVVLATGWR GEANFINPMC GSGTLAIEAA LIGLNRAPGL LRSNFGFMHI KGFPESAWNE
LREKAKQQSR RSIPGRIIAT DIDPDAVEAA RKNATTAGVE HLIEFRVCDF RDTPLPGNGM
IVMNPPYGER MGEIAKLEGL YKDIGDFFKQ KCKGYTGYVF TGNPALSKKV SLKPKRSIPF
FNSGIECRLL EYELYEGTRK VKKMKTTG
//
