ID A0A1G1JTS7_9BACT Unreviewed; 710 AA.
AC A0A1G1JTS7;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=FtsK domain-containing protein {ECO:0000259|PROSITE:PS50901};
GN ORFNames=A2987_03775 {ECO:0000313|EMBL:OGW84044.1};
OS Omnitrophica bacterium RIFCSPLOWO2_01_FULL_45_10.
OC Bacteria; Candidatus Omnitrophota.
OX NCBI_TaxID=1801826 {ECO:0000313|EMBL:OGW84044.1, ECO:0000313|Proteomes:UP000176340};
RN [1] {ECO:0000313|EMBL:OGW84044.1, ECO:0000313|Proteomes:UP000176340}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- SUBUNIT: Homohexamer. Forms a ring that surrounds DNA.
CC {ECO:0000256|ARBA:ARBA00025923}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FtsK/SpoIIIE/SftA family.
CC {ECO:0000256|ARBA:ARBA00006474}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGW84044.1}.
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DR EMBL; MHFL01000037; OGW84044.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G1JTS7; -.
DR STRING; 1801826.A2987_03775; -.
DR Proteomes; UP000176340; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR CDD; cd01127; TrwB_TraG_TraD_VirD4; 1.
DR Gene3D; 3.30.980.40; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR025199; FtsK_4TM.
DR InterPro; IPR041027; FtsK_alpha.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR018541; Ftsk_gamma.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR22683:SF41; DNA TRANSLOCASE FTSK; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR Pfam; PF13491; FtsK_4TM; 1.
DR Pfam; PF17854; FtsK_alpha; 1.
DR Pfam; PF09397; FtsK_gamma; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00843; Ftsk_gamma; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50901; FTSK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 51..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 118..135
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 142..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 377..567
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT BINDING 394..401
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 710 AA; 78226 MW; 72B6E638AC7E536E CRC64;
MDKTRWNEIQ AVIFFAVAIL VFTSLATFDF SDLGLFTSKI NEPIRNLAGL FGAYLGAILF
FVMGLSAYTI PFLILSWAAA RVTGITPQKL HFKVFGTFFL ILASSSIASV IGRGDSAFRF
RLGGIVGLAF SDFLIKYLGR GGALIVILVL FLLSVLLATE FLLLPFLSGI LRRWKGFVSN
LKGRTLKEEG TPVLTIRRER REEPLKGGES PVKKPPALKK EIEVVKKIKI SASEPPVGDG
WKFPGLDLLE SPPPIEERKI KENFESSARI LEETLRDFDI ESKVVEINKG PVITRYELEP
APGVKVHRIT SLSDNIALAM KAQSVRIVAP IPGKGTIGVE VPNSSSALVY LKEVLDSKEY
KEFDSKLKLA IGKDIAGAPV VADLSTMPHL LIAGATGSGK TVCVNAIVTS LLFNSSPDEV
RFIMIDPKRV ELAVFNDLPH LLSPVVTDMK KVSTTLEWVV AEMESRYEMF AKSGVRNIDL
YNERIAKDGN AKLPYIIVII DELADLMMVS QDQVEGAITR LAQLSRAVGI HIIIATQRPS
VDVITGVIKA NFPARISFKV ASKVDSRTVL DINGADKLLG RGDMLFIEPG ASRPIRAQCS
LISDKEIEKI TNSIKSQRGP SYVEEILESE KKAAFRKFEK DEVYEEAVKL VLETRQASVS
ILQRRLGLGY TRAARLIDMM EDEGVVGPYQ GSKPRDVLLS LEAYQTKNAK
//
