ID A0A1G1JZ29_9BACT Unreviewed; 590 AA.
AC A0A1G1JZ29;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=Penicillin-binding protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=A3C35_06725 {ECO:0000313|EMBL:OGW85884.1};
OS Omnitrophica bacterium RIFCSPHIGHO2_02_FULL_46_11.
OC Bacteria; Candidatus Omnitrophota.
OX NCBI_TaxID=1801820 {ECO:0000313|EMBL:OGW85884.1, ECO:0000313|Proteomes:UP000176909};
RN [1] {ECO:0000313|EMBL:OGW85884.1, ECO:0000313|Proteomes:UP000176909}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGW85884.1}.
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DR EMBL; MHFF01000046; OGW85884.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G1JZ29; -.
DR STRING; 1801820.A3C35_06725; -.
DR Proteomes; UP000176909; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 1.10.150.770; -; 1.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 41..186
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 232..540
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
FT REGION 551..590
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 560..590
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 590 AA; 65771 MW; 212C923EAA8ED398 CRC64;
MNLAILATFP LIVYQLFRLT VQNHDFLRQY ARRQHNIVVE IPPERGAILD RNLKEFATNL
KVPSIYAVPR LMLEKDRKVA AEKLSKVLGL SKPFLLERFS RDKAFVWIKR RTSVAEAEAV
RKLKSANIGI TYEPKRFYPQ GEMLAHVIGF CNIDNIGQEG LELLYERRLA GRLGYRYTKR
DAFGREMIAL EEKLVPPLNG ARLILTIDQY IQYVTEQALD DAFKKRHAKG ATAIVMNPKT
GEILAMASRP TFDPNRLSES DAAHRRNRPI TDIFEPGSVF KIVTAAAALN EGKVTLQDTF
NCENGEWQVR ASRVIHDVHP YGRLSFPEVL IKSSNIGTVK IAMRLGEEPL YRYIKQFGFG
EKTGIDFPGE VSGILHPLNK WSKVSITSIP YGQEVAATAL QMLRAIAVIA NGGHLVKPYL
LKEIQDANGV SLMKNEPIVS EESILKPEVV ASMNEILQRV VSEGTGTSAQ IEGIRIAGKT
GTAQKLEPGG GYSHRHFIGS FIGYAPAEDP MLAMIVSIDD PRPYYYGGTV AAPVFKDVIE
RSLIHLGYVP EKKPAKKTDQ KSQAISGRAS SPSLPRNPQP EFQGVSPQVR
//
