ID A0A1G1KCH3_9BACT Unreviewed; 558 AA.
AC A0A1G1KCH3;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=Penicillin-binding protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=A3D28_04400 {ECO:0000313|EMBL:OGW90560.1};
OS Omnitrophica bacterium RIFCSPHIGHO2_02_FULL_63_14.
OC Bacteria; Candidatus Omnitrophota.
OX NCBI_TaxID=1801824 {ECO:0000313|EMBL:OGW90560.1, ECO:0000313|Proteomes:UP000179358};
RN [1] {ECO:0000313|EMBL:OGW90560.1, ECO:0000313|Proteomes:UP000179358}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGW90560.1}.
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DR EMBL; MHFJ01000073; OGW90560.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G1KCH3; -.
DR Proteomes; UP000179358; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 1.10.150.770; -; 1.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 40..185
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 229..534
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 558 AA; 61334 MW; 46E37552DE44EC86 CRC64;
MCFLAALTLL LARLAYLQLF QSSKFVSLVQ NQSRAIIDMQ PARGRILDRR NRELASDVRL
NSLYAIAREI PARRKPELAT RLAGILGSSR GEILRRLQKD KMKIWLKRKI TAPQAEQVTR
LGLRQLGFEK ESLRVYPKGQ TACHLLGFTD IDNNGLEGIE LRYNSFLKGV PGWRLAQRDA
HQRELVSKEL RMVPPVDGYS IRLTIDEVIQ AIAEKELNEA CRKYRAAGGS VIVLDPATGD
VLAMAVYPAY DPNDAKRSSP EARRNRAITD LFEPGSVFKM ITLAGIIENK TFPLSEMFHC
ENGSWAVAGK VLHDHRGHGR MPFREVIEKS SNIGTVKGAM RLGADKLYHT IRSFGFGQAT
GIGLAGEIGG IVPHPKHWSR SSIINIPIGH GIAVTPLQLA AAFGAVANDG VLMRPRILIA
VEDNEGKTIR SYPPEAVRQA VSKETALQVR TVLEGVVSRG TGKKAQVPGF KAAGKTGTAQ
KILPDGKYSH SDFIASFVGF VPYDRPKLVI AVSVDEPRPV YYGGEVAAPV FSRVAAGVLA
YWRINETRIP AEVLPRAA
//
