ID A0A1G1KR78_9BACT Unreviewed; 436 AA.
AC A0A1G1KR78;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=UDP-N-acetyl-D-glucosamine dehydrogenase {ECO:0000313|EMBL:OGW95450.1};
GN ORFNames=A3G33_10765 {ECO:0000313|EMBL:OGW95450.1};
OS Omnitrophica bacterium RIFCSPLOWO2_12_FULL_44_17.
OC Bacteria; Candidatus Omnitrophota.
OX NCBI_TaxID=1801832 {ECO:0000313|EMBL:OGW95450.1, ECO:0000313|Proteomes:UP000178187};
RN [1] {ECO:0000313|EMBL:OGW95450.1, ECO:0000313|Proteomes:UP000178187}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- SIMILARITY: Belongs to the UDP-glucose/GDP-mannose dehydrogenase
CC family. {ECO:0000256|PIRNR:PIRNR000124}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGW95450.1}.
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DR EMBL; MHFR01000063; OGW95450.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G1KR78; -.
DR Proteomes; UP000178187; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR017476; UDP-Glc/GDP-Man.
DR InterPro; IPR014027; UDP-Glc/GDP-Man_DH_C.
DR InterPro; IPR036220; UDP-Glc/GDP-Man_DH_C_sf.
DR InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer.
DR InterPro; IPR001732; UDP-Glc/GDP-Man_DH_N.
DR InterPro; IPR028359; UDP_ManNAc/GlcNAc_DH.
DR NCBIfam; TIGR03026; NDP-sugDHase; 1.
DR PANTHER; PTHR43491; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR PANTHER; PTHR43491:SF1; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR Pfam; PF00984; UDPG_MGDP_dh; 1.
DR Pfam; PF03720; UDPG_MGDP_dh_C; 1.
DR Pfam; PF03721; UDPG_MGDP_dh_N; 1.
DR PIRSF; PIRSF500136; UDP_ManNAc_DH; 1.
DR PIRSF; PIRSF000124; UDPglc_GDPman_dh; 1.
DR SMART; SM00984; UDPG_MGDP_dh_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52413; UDP-glucose/GDP-mannose dehydrogenase C-terminal domain; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 333..427
FT /note="UDP-glucose/GDP-mannose dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00984"
SQ SEQUENCE 436 AA; 48244 MW; 1C89871C9CD36B72 CRC64;
MQTSTQQQLN EKIRTKTIRA GIIGLGYVGL PLAVEFARAG VEVIGIDIDS KKVTSVQQGK
SYILDVKESD VATFVKREKL HATTDFSVIA NLDTVNICVP TPLRKSKDPD ISYIVAATQE
IAKYVHPGML IILESTTYPG TTEEVILPML EEKGLKVGKD FFLAFSPERV DPGNPKYHTG
NIPKVVGGVT KECTELAAAF YGLVMDTVCR VKSASSAEMV KLLENTFRSV NIGLVNELCQ
MCAKMNLDVW EIIDAASTKP FGYMPFYPGP GIGGHCIPLD PHYLAWKARS YGFAPRFIEL
ASEVNESMPE FVVRKAQDVL NEKGRALKGA NVRILGVTYK KNISDQRESP AHSIIEILLK
KGAYVSCSDP FVPEYQVEDK SFKSLPVDEQ SKDVDLAILV TDHDQFDKQK LLDTFKTILD
TRNAFRDNPS AKVVKI
//
