ID A0A1G1KU23_9BACT Unreviewed; 797 AA.
AC A0A1G1KU23;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=DNA internalization-related competence protein ComEC/Rec2 {ECO:0008006|Google:ProtNLM};
GN ORFNames=A3G33_00305 {ECO:0000313|EMBL:OGW96406.1};
OS Omnitrophica bacterium RIFCSPLOWO2_12_FULL_44_17.
OC Bacteria; Candidatus Omnitrophota.
OX NCBI_TaxID=1801832 {ECO:0000313|EMBL:OGW96406.1, ECO:0000313|Proteomes:UP000178187};
RN [1] {ECO:0000313|EMBL:OGW96406.1, ECO:0000313|Proteomes:UP000178187}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGW96406.1}.
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DR EMBL; MHFR01000050; OGW96406.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G1KU23; -.
DR Proteomes; UP000178187; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 43..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 66..82
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 265..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 297..318
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 365..384
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 404..426
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 438..459
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 465..486
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 498..520
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 526..544
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 44..193
FT /note="DUF4131"
FT /evidence="ECO:0000259|Pfam:PF13567"
FT DOMAIN 243..518
FT /note="ComEC/Rec2-related protein"
FT /evidence="ECO:0000259|Pfam:PF03772"
SQ SEQUENCE 797 AA; 90278 MW; DC886E983558C647 CRC64;
MKIQNSQIIK DNRKRLLSVP PLIYLSLAFC TGIAFAYKIE VSFELISFAV AFLFMIYILT
RFRGNIIFRV LLFFSLGMLF GIDSRNVSNS HVVRTHFEGK TTIEGVVVDD PEIVTRGKKE
TVSFVLKLDS FYEQGEIHRA SGNIRVVLFN PRREIGFGER VRLRGMLEKP KRSTNFHAFD
YSGYLAKRGI YRIFQGIGQY SVLKQIKEPG VSWLLTIHKL RVNAKKQLDR LLEKPYSDLA
AGLLLGFRKN IPRHITDEFI KTGTAHFLSI SGLHISLLGG FFYLLGRFFR IPRKLNLFLT
MGLILLYCVM AGAAIPVLRS GIMGVMVLAG FLLGHERNLG QAFFFSFLLL LVWDPASLFD
VSFQLSFISV AALVFIFPKI DIFLGNPPQI KNNIDFLARV RYEIRSTIQA SLAVMIAIFP
VLIWYFHLFS LIGFIANMFV IPVGNTAIIT TLFLMVIALT SQPVAAFFVF VPEALFKCLC
MIVHVLSQVP FGYFYLPVPH WSFFIVYYSI LLLWFSSWFV PVYRSVRFGL IGGLVGITFL
YFIFSSPRTF RFVVFDVGKT DAAFVQFSSR SNCLINSGRS FPGDQAYWTI QPFLSASGVQ
IINGILFSVV DGKHSGGLQT LAKYFRIQNI WYPRDTAPDK KIKYIDALSG PRIKKLPVAE
GERLGFGETE GIEFIESGLR KGNVFHIFDG AVKILYLNSV LPEVFSSLIE IYKQKCQVLI
LPDHPNGISA EERSFLEAVS PQYIVLNQRE GILSLRQDLK KVTKAVLLFI AETGAIEFYR
EGTDLLYKTV VDSSQKG
//
