ID A0A1G1M7Q9_9BACT Unreviewed; 473 AA.
AC A0A1G1M7Q9;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE RecName: Full=Ferrous iron transport protein B {ECO:0000256|RuleBase:RU362098};
DE Flags: Fragment;
GN ORFNames=A2351_08590 {ECO:0000313|EMBL:OGX12960.1};
OS Omnitrophica bacterium RIFOXYB12_FULL_50_7.
OC Bacteria; Candidatus Omnitrophota.
OX NCBI_TaxID=1801835 {ECO:0000313|EMBL:OGX12960.1, ECO:0000313|Proteomes:UP000177505};
RN [1] {ECO:0000313|EMBL:OGX12960.1, ECO:0000313|Proteomes:UP000177505}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- FUNCTION: Probable transporter of a GTP-driven Fe(2+) uptake system.
CC {ECO:0000256|RuleBase:RU362098}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|RuleBase:RU362098}; Multi-pass membrane protein
CC {ECO:0000256|RuleBase:RU362098}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
CC {ECO:0000256|RuleBase:RU362098}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU362098}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGX12960.1}.
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DR EMBL; MHFU01000066; OGX12960.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G1M7Q9; -.
DR STRING; 1801835.A2351_08590; -.
DR Proteomes; UP000177505; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR InterPro; IPR003373; Fe2_transport_prot-B.
DR InterPro; IPR011640; Fe2_transport_prot_B_C.
DR InterPro; IPR011642; Gate_dom.
DR NCBIfam; TIGR00437; feoB; 1.
DR PANTHER; PTHR43185:SF1; FE(2+) TRANSPORTER FEOB; 1.
DR PANTHER; PTHR43185; FERROUS IRON TRANSPORT PROTEIN B; 1.
DR Pfam; PF07664; FeoB_C; 1.
DR Pfam; PF07670; Gate; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU362098};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|RuleBase:RU362098};
KW Iron transport {ECO:0000256|ARBA:ARBA00022496,
KW ECO:0000256|RuleBase:RU362098};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362098};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362098};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362098};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU362098}.
FT TRANSMEM 39..60
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362098"
FT TRANSMEM 95..119
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362098"
FT TRANSMEM 188..208
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362098"
FT TRANSMEM 214..233
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362098"
FT TRANSMEM 271..290
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362098"
FT TRANSMEM 413..435
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362098"
FT TRANSMEM 442..464
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362098"
FT DOMAIN 103..197
FT /note="Nucleoside transporter/FeoB GTPase Gate"
FT /evidence="ECO:0000259|Pfam:PF07670"
FT DOMAIN 215..267
FT /note="Ferrous iron transport protein B C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07664"
FT DOMAIN 272..442
FT /note="Nucleoside transporter/FeoB GTPase Gate"
FT /evidence="ECO:0000259|Pfam:PF07670"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:OGX12960.1"
SQ SEQUENCE 473 AA; 52605 MW; 02EA3C2B79F77918 CRC64;
EAEKRYKLIE SVCCEALKKN PVKRLSVSEK LDRVMTHRIW GLAIFVGVMG FIFQSIFTWA
SFPTDLISAG IEKLSIFAQG ILPDGALESL VVDGMIAGVG NVVVFLPQIM LLFFFIALFE
DVGYMARAVF VLDRLMKKVG LNGKAFLPLL SGFACAIPGI MATRTIEDRN DRLATILITP
LMSCSARLPV YTLMIAAFIP ALPVLPFLDL KGFILLSMYV LSIASGLGMA ALFRKTFLKG
NRMPFIFELP PYRIPHMKTV FLTMWDRAKA FLLRAGGIIF CLSIVLWFLV NYPKNAELEA
RFHQDETTAE QILKGEALQN RLSEIDHEKK NQLILSSYAG RAGKFIEPAI KPLGFNWEIG
IGLVASFAAR EVIVSTLAII HNVGSDEGVS TDLIQTLQKE KDPETGLPKY TPLIAVSLMV
FYVLAMQCLS TVAVVQRETG TWTWPLFMIL YMTSLAWAGS FIVYQGGRLL GFQ
//
